Results 61 to 70 of about 9,553 (194)

Traditional Chinese Medicine Formulas in Delaying Aging: From Theoretical Foundations to Molecular Mechanisms and Translational Perspectives

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Aging is a systemic decline in physiological integrity, driving chronic diseases such as neurodegeneration, cardiovascular disorders, and metabolic syndromes. Rapid global population aging urgently demands effective interventions. Traditional Chinese medicine (TCM) formulas, characterized by multi‐component, multi‐target, and multi‐pathway ...
Chenrong Jin, Ding Du, Xiaorui Yu, Xiaoyan Ji, Xiuyun Zhang, Anning Li, Shuang Zu, Bo Qu, Daqing Zhao, Dianpeng Wu, Meichen Liu   +10 more
wiley   +1 more source

Hepatoprotective Iridoid Glycosides from the Roots of Rehmannia glutinosa

, 2016
Eleven new iridoid glycosides, rehmaglutosides A–K (1–11), together with 20 known analogues were isolated from the air-dried roots of Rehmannia glutinosa.
Zhi-You Hao (1479349), Dong Liang (120479), Yan Wang (15435), Qing-Jian Zhang (2039830), Ruo-Yun Chen (743339), De-Quan Yu (723013), Huan Luo (244018), Yan-Fei Liu (1404967), Chun-Lei Zhang (292929)   +8 more
core   +1 more source

Lauric acid and 2, 6-ditertbutyl phenol, two major allelochemicals from Rehmannia glutinosa inhibiting the germination of succeeding crop, Sesamum indicum [PDF]

, 2015
Rehmannia glutinosa Libosch, a well known herb for Chinese traditional medicine, and sesame are two main crops in Northwestern Henan, China. It has been known however that, a rotation of these two crops, for example, cultivation of sesame preceeded with ...
Liu, X, Gao, Y, Wu, K, Wang, MD, Jia, X, Chen, H   +5 more
core   +1 more source

Clinical Efficacy and Mechanisms of ZiyuShuang, an Anti‐Skin Aging Formula Identified Through Network Medicine Framework Analysis

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Skin aging, a key aspect of physiological decline, markedly affects appearance, making strategies to delay it vital for quality of life. Materials and Methods We applied network medicine analysis to screen herbal medicines from the TCMSP database, yielding an anti‐skin aging formula, ZiYuShuang (ZYS).
Yingpeng Tong, Xiangmei Ni, Xinnan Jiang, Ru Zhang, Pengcheng Guo, Chunbo Feng, Jianxin Wang   +6 more
wiley   +1 more source

Transcriptome Analysis Provides Insights into Catalpol Biosynthesis in the Medicinal Plant Rehmannia glutinosa and the Functional Characterization of RgGES Genes. [PDF]

Genes (Basel)
Rehmannia glutinosa, a member of the Scrophulariaceae family, has been widely used in traditional Chinese medicine since ancient times. The main bioactive component of R. glutinosa is catalpol.
Li Y, Zhai X, Ma L, Zhao L, An N, Feng W, Huang L, Zheng X.   +7 more
europepmc   +2 more sources

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche, Namdev More, Tiffany Lee, Mia Orr, Anne Camus, Devina Purmessur, Sarah E. Gulbrand, Nadeen O. Chahine, Lara Silverman, Dmitriy Sheyn   +9 more
wiley   +1 more source

Study on tuberization of Rehmannia glutinosa (Gaertn.) Libosch.

Vietnam Journal of Biotechnology, 2020
Rehmannia glutinosa (Gaertn.) Libosch. is an herbal plant, which belongs to the Srcophulariaceae family, containing the main active ingredients such as catalpol and verbacoside in its root tubers. In traditional medicine, R. glutinosa tubers have been used in the fresh or dried tuber root or the prepared rehamannia root.
Vu Hoai Sam, Nguyen Thi Xuyen, Nguyen Thi Huong, Duong Thi Ngoc Anh, Nguyen Minh Tuyen, Nguyen Duy Phuong, Phan Thuy Hien   +6 more
openaire   +2 more sources

Mechanism of Gu‐Ben‐Hua‐Shi (AESS) Formula Regulating Autophagy Through Hippo‐YAP Pathway in Restoring the Skin Barrier in Atopic Dermatitis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by skin barrier dysfunction and immune balance disorders. Currently, drugs for repairing the skin barrier in AD are limited. The gu‐ben‐hua‐shi formula (AESS) has been shown to regulate Th1/Th2/Th17/Treg imbalance with good clinical effect.
Xin Ma, Yiting Huang, Xiao Lv, Xiumei Mo, Junfeng Liu, Fenggen Yan, Siqi Ye, Yu Zhang, Dacan Chen, Jinjing Jia   +9 more
wiley   +1 more source