Results 81 to 90 of about 82,507 (301)
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
Advanced Science, EarlyView.Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang +6 more
wiley +1 more source
Oral Rehydration; its historical review and perspectives
, 2003 P(論文)Oral rehydration therapy(以下、ORT)は、成人コレラ患者の治療法として普及後、乳児下痢症による脱水症の治療法としての効果も認められ、特にWHOやUNICEFの指導と推進により発展途上国で多くの乳児を救命している。また、ORTは脱水症の予防としても有効である。このORTに用いる溶液であるoral rehydration solution(以下、ORS)は、水、糖、電解質の混合液であり、腸粘膜における糖とナトリウム(以下、Na)吸収のメカニズムが理論的に立証されている ...
杉浦, 令子, 村田, 光範
core
Advanced Science, EarlyView.ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan +12 more
wiley +1 more source
REHYDRATING OF DRY WHEY OPTIMIZATION BY CAVITATION DISINTEGRATION
Вестник Северо-Кавказского федерального университета, 2022 The article presents the results Rehydration of dry whey optimization by cavitation disintegration. Designate the optimal recovery modes of dry whey, required for the formation of high-quality properties (рН, viscosity, water activity, redox, density ...
Konstantin Kostenko +3 more
doaj
BMC Public Health, 2012 Background Rehydration therapy is a critical intervention to save the lives of children during the episodes of diarrhea. However, millions of children die every year due to failure to replace fluid effectively. The objective of this study was to identify
Mengistie Bezatu +2 more
doaj +1 more source
Advanced Science, EarlyView.HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
Shuitu Baochi Xuebao[Objective] Crops often suffer from interval drought and rehydration (rainfall or irrigation) during the whole growth period, especially in arid and semi-arid areas.
LI Taotao +6 more
doaj +1 more source
, 2021 A multi-centre open-label phase II randomised controlled trial evaluated two rehydration strategies in 122 Ugandan/Kenyan children aged 60 days to 12 years with severe dehydration secondary to gastroenteritis.
Obonyo, Nchafatso +12 more
core +1 more source