Could calcitonin gene‐related peptide inhibitors prevent status epilepticus?
Abstract Calcitonin gene‐related peptide (CGRP) inhibitors modulate pain and neuroinflammation, a recognized contributor to epileptogenesis and status epilepticus (SE). We examined the association between CGRP inhibitor use and SE hospitalization in epilepsy patients with comorbid migraine.
Michael Nsaka +6 more
wiley +1 more source
Understanding disparities in autism diagnosis and care: A socioecological perspective. [PDF]
Bala A +6 more
europepmc +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Availability and public reimbursement of early breast cancer care across European expert centres: a PORTRAIT from an EUSOMA initiative. [PDF]
Bonci EA +7 more
europepmc +1 more source
ABSTRACT Objectives Dravet syndrome (DS) is a severe, drug‐resistant developmental and epileptic encephalopathy (DEE) that requires polytherapy for adequate seizure control. The need to combine multiple antiseizure medications (ASMs), together with variability in seizure types, safety considerations, and evolving patient needs, makes treatment ...
Elaine Wirrell, Joseph Sullivan
wiley +1 more source
Accelerating AI in clinical care: policy priorities of the 2025 HHS request for information. [PDF]
Klonoff DC +3 more
europepmc +1 more source
Genetic testing practices across European epilepsy centers: An ERN EpiCARE survey
Abstract Objective Genetic testing plays an increasing role in the diagnostic pathway for rare and complex epilepsies. However, significant heterogeneity persists in access, implementation, and interpretation across Europe. This study aimed to assess genetic testing practices, accessibility, and challenges across expert epilepsy centers within the ...
Sébile Tchaicha +11 more
wiley +1 more source
Patient-operated imaging for clinical assessment: regulatory and reimbursement challenges in European health systems. [PDF]
Fenton C, Tibi C, Glazer J, Prisant N.
europepmc +1 more source
Cumulative electroconvulsive therapy sessions and focal epilepsy: A nationwide cohort study in Japan
Abstract Objective Electroconvulsive therapy (ECT) is widely used for severe psychiatric disorders, yet concerns remain regarding possible epileptogenic effects associated with prolonged or repeated exposure. We examined the association between cumulative ECT sessions and focal epilepsy in a nationwide Japanese cohort.
Masahiro Hata +4 more
wiley +1 more source

