Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin +7 more
wiley +1 more source
A Cost Analysis of Carpal Tunnel Procedures Performed in an Office Procedure Room Versus a Hospital Operating Room in a Rural Midwest Health System. [PDF]
Hurley LJ, Hardie KA, Van Demark RE.
europepmc +1 more source
Did the French pregnancy pictogram change antiseizure medication use during pregnancy?
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo +7 more
wiley +1 more source
Channeling Patient Flow in China: An Agent-Based Model of Insurance Reimbursement and Hierarchical Care. [PDF]
Zhao N +6 more
europepmc +1 more source
Abstract Objective Inclusion and exclusion criteria of clinical trials for seizures aim to select representative participants with a high enough seizure frequency to evaluate the efficacy of treatment in a relatively short double‐blind period. To inform the selection of seizure frequency‐based inclusion criteria, we evaluated the association between ...
Wesley T. Kerr +5 more
wiley +1 more source
BRCA1/2, PALB2 mutations and first-line CDK4/6 inhibitor efficacy in HR+ metastatic breast cancer. [PDF]
Guinel T +16 more
europepmc +1 more source
Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie +10 more
wiley +1 more source
Conceptualizing and measuring integration of telehealth and in-person services from the provider's perspective: development of the integration of telehealth and in-person services (ITIPS) survey. [PDF]
Shea CM +3 more
europepmc +1 more source
Shared visits vs incident-to billing for pharmacy services. [PDF]
Dietrich E, Rosario E, Panella SM.
europepmc +1 more source
Uncompensated Hospitalizations in Children's Hospitals.
Gay JC, Synhorst DC, Grills N, Hall M.
europepmc +1 more source

