Modelling, Analysis, Observability and Identifiability of Epidemic Dynamics with Reinfections [PDF]
We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an image of the same infection process, but counting also the reinfections.
arxiv
Network infection source identification under the SIRI model [PDF]
We study the problem of identifying a single infection source in a network under the susceptible-infected-recovered-infected (SIRI) model. We describe the infection model via a state-space model, and utilizing a state propagation approach, we derive an ...
Harilal, Athul+3 more
core +1 more source
Developing and testing accelerated partner therapy for partner notification for people with genital Chlamydia trachomatis diagnosed in primary care: a pilot randomised controlled trial [PDF]
Background Accelerated partner therapy (APT) is a promising partner notification (PN) intervention in specialist sexual health clinic attenders. To address its applicability in primary care, we undertook a pilot randomised controlled trial (RCT) of two
Althaus+36 more
core +6 more sources
Optimal control for a tuberculosis model with reinfection and post-exposure interventions [PDF]
We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions, considering reinfection and post-exposure interventions. They depend on the parameters of the model and reduce effectively the number of active infectious and ...
arxiv +1 more source
Cost effectiveness analysis of optimal control measures for tuberculosis [PDF]
We propose and analyse an optimal control problem where the control system is a mathematical model for tuberculosis that considers reinfection. The control functions represent the fraction of early latent and persistent latent individuals that are treated.
arxiv +1 more source
Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting.
Eckhoff, Philip+2 more
core +1 more source
Observed Reductions in Schistosoma mansoni Transmission from Large-Scale Administration of Praziquantel in Uganda: A Mathematical Modelling Study [PDF]
To date schistosomiasis control programmes based on chemotherapy have largely aimed at controlling morbidity in treated individuals rather than at suppressing transmission.
A Fenwick+72 more
core +3 more sources
Frequency and risk factors for incident and redetected Chlamydia trachomatis infection in sexually active, young, multi-ethnic women: a community based cohort study. [PDF]
OBJECTIVE: To investigate the frequency and risk factors for incident and redetected Chlamydia trachomatis infection in sexually active, young, multi-ethnic women in the community. DESIGN: Cohort study.
Aghaizu, A+8 more
core +2 more sources
Parasite infection in a cell population with deaths and reinfections [PDF]
We introduce a model of parasite infection in a cell population, where cells can be infected, either at birth through maternal transmission, from a contact with the parasites reservoir, or because of the parasites released in the cell medium after the lyses of infected cells.
arxiv
Immune Responses in Human Necatoriasis: Association between Interleukin-5 Responses and Resistance to Reinfection [PDF]
Cytokine and proliferative responses to Necator americanus infection were measured in a treatment-reinfection study of infected subjects from an area of Papua New Guinea where N. americanus is highly endemic.
Brown, A.P.+4 more
core