Results 91 to 100 of about 523,767 (236)
An Overview on ZnO Reinforced Composites
Zinc oxide reinforced composites are a promising class of materials with a wide range of potential applications. By combining ZnO with other materials, scientists and engineers can achieve advanced functionalities that go beyond the properties of the ...
Andreea Elena ONACHE (VIJAN) +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
REINFORCEMENT OF INHIBITION [PDF]
A differential‐reinforcement‐of‐other‐behavior (DRO) schedule with trials and delayed reinforcement was investigated. Periodically a wheel was briefly available to rats, followed six seconds later by brief availability of a bar. Variable‐ratio food reinforcement of wheel turns was adjusted to give 95% turns.
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Behaviour of GFRP rebars reinforced concrete elements under elevated temperature and fire [PDF]
PhDIn general, it is expected that concrete structures using Glass Fibre Reinforced Plastic (GFRP) rebars as reinforcement could have improved durability compared to normal steel reinforcement because of the corrosion resistance of the rebar. However,
Dezfouli, Abdolkarim Abbasi
core +2 more sources
SEISMIC RESISTANCE OF REINFORCED CONCRETE COLUMNS UNDER COMBINED SPECIAL ACTIONS [PDF]
The study addresses the seismic resistance of reinforced concrete columns that have been damaged by the corrosion of their steel reinforcement and the concrete itself, and that have experienced the effects of high temperatures resulting from fire ...
Ashot G. Tamrazyan +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
In the domain of modern timber structural systems, timber frame constructions distinguish themselves as preferred and commonly used building methods. Their appeal arises from their architectural adaptability and their distinctive attributes, which enable
Yasemin Şi̇mşek Türker
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

