Results 111 to 120 of about 1,593,393 (303)

Hamiltonian Monte Carlo Without Detailed Balance [PDF]

, 2016
We present a method for performing Hamiltonian Monte Carlo that largely eliminates sample rejection for typical hyperparameters. In situations that would normally lead to rejection, instead a longer trajectory is computed until a new state is reached ...
DeWeese, Michael R., Mudigonda, Mayur, Sohl-Dickstein, Jascha   +2 more
core   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Experiencing discrimination increases risk taking. [PDF]

, 2013
Prior research has revealed racial disparities in health outcomes and health-compromising behaviors, such as smoking and drug abuse. It has been suggested that discrimination contributes to such disparities, but the mechanisms through which this might ...
Jamieson, Jeremy P, Koslov, Katrina, Mendes, Wendy Berry, Nock, Matthew K   +3 more
core   +1 more source

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

Outcome of Solid Organ Transplantation in Patients With Intellectual Disability: A Systematic Literature Review

Transplant International
Access to solid organ transplantation in patients with intellectual disability is associated with health inequities due to concerns about treatment adherence, survival rates, and post-transplant quality of life.
Ingeborg de Rover, Lara Orlandini, Sarwa Darwish Murad, Wojciech G. Polak, Jane Hartley, Khalid Sharif, Dimitri Sneiders, Hermien Hartog, Hermien Hartog, Hermien Hartog   +9 more
doaj   +1 more source

Self‐Assembled Nanoclay Gel With Spheroid MSC‐Derived Exosome Mimetics to Integrate Demineralized Bone Matrix and Noggin‐Targeting miRNA for Synergistic Osteogenesis

Advanced Functional Materials, EarlyView.
We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu, Zhi Li, Minjee Kang, Ruoyu Sheng, Bing Han, Yiqing Chen, Tara Aghaloo, Min Lee   +7 more
wiley   +1 more source

Pharmacodynamic monitoring by residual gene expression of the nuclear factor of activated T cell-regulated genes in lung transplant recipients and its correlation with tacrolimus blood levels

Frontiers in Immunology
IntroductionTrough blood levels (C0) of tacrolimus are used to adjust drug dosage, but they do not consistently correlate with clinical outcomes. Measurement of residual gene expression of nuclear factor of activated T cell (NFAT)-regulated genes (NFAT ...
Meritxell Boada-Pérez, Meritxell Boada-Pérez, Victoria Ruiz de Miguel, Marta Erro, Piedad Ussetti, Myriam Aguilar, Raquel Castejón, Silvia Rosado, Roser Escobar-Fornieles, Eva Revilla-López, Carlos Bravo, Carlos Bravo, Berta Sáez-Giménez, Berta Sáez-Giménez, Marta Zapata-Ortega, Marta Zapata-Ortega, Yolanda Villena-Ortiz, Jaume Vima-Bofarull, Víctor Monforte, Víctor Monforte, Susana Gómez-Ollés, Susana Gómez-Ollés   +21 more
doaj   +1 more source

Structural and Chemical Engineering of Sub‐Nanochannel Membranes Toward Ion Selectivity

Advanced Functional Materials, EarlyView.
This review summarizes recent advances in structural and chemical engineering of sub‐nanochannels for ion selectivity. We first introduce fundamental ion transport mechanisms within sub‐nanochannels, followed by strategies to tune pore size, geometry, and surface functionalities, categorized into charge‐based, ion‐recognition, hydrophilic bonding, and ...
Yuyu Su, Huacheng Zhang, Tamar L. Greaves, Qi Han, Weiwei Lei, Dan Liu   +5 more
wiley   +1 more source

Antibody-Mediated Rejection in Liver Transplantation: Immuno-Pathological Characteristics and Long-Term Follow-Up

Transplant International
The diagnosis of liver antibody-mediated rejection (AMR) is challenging and likely under-recognized. The association of AMR with donor-specific antibodies (DSA), and its clinical course in relation to pathologic findings and treatment are ill defined. We
Luca Cicalese, Zachary C. Walton, Xiaotang Du, Rupak Kulkarni, Suimin Qiu, Mohamed El Hag, Heather L. Stevenson   +6 more
doaj   +1 more source

An Equal Opportunity Rejection

, 2013
Let’s talk about applications. We’ve all been there. You write your application, work on draft after draft and then you send it all off to the college or job of your dreams. And you wait…and wait…and wait.
Patterson, Katherine M.
core