Results 171 to 180 of about 317,328 (219)

Shrinking Giants: On the Feasibility of Downsizing Hepatocellular Carcinoma with Immunotherapy Prior to Liver Transplantation. [PDF]

J Clin Med
Prejac J, Kekez D, Lučev H, Ćutić B, Domislović V, Šeša V, Adžić G, Golčić M.   +7 more
europepmc   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Blood vessels as primary site of rejection in murine lung transplantation. [PDF]

Transpl Int
Kaes J, Hooft C, Jin X, Heigl T, Liu H, Pollenus E, Prenen F, Beeckmans H, Kerckhof P, Vanstapel A, Van Slambrouck J, Mercurio M, Zapata-Ortega M, Aerts G, Geudens V, Vermaut A, Vanvuchelen L, Somers A, Verbeylen L, Vanluyten C, Barbarossa A, Mohamady Y, Özsoy B, Zajacova A, Tielemans B, Yildirim AO, Bos S, De Sadeleer L, Godinas L, Rojas Quintero J, Polverino F, Van den Steen PE, Ceulemans LJ, Vos R, Vanaudenaerde BM.   +34 more
europepmc   +1 more source

From Materials to Medical Images: Translating Perovskite‐Based X‐Ray Detectors Toward Clinical Imaging

Advanced Science, EarlyView.
This review examines perovskite‐based X‐ray detectors from a materials‐to‐medical‐images perspective. Recent progress in perovskite‐based X‐ray detectors is discussed with emphasis on their relevance to clinical imaging. The key barriers to clinical implementation are analyzed.
Sibin Wang, Yongrui Yang, Kun Zhang, Xiaojuan Lu, Hong Yin, Yali Qiao, Xiaojia Zheng, Xiao Zhang, Yanlin Song   +8 more
wiley   +1 more source

Photobiomodulation in acute rejection of fetal intestinal grafts: morphological aspects and lymphocyte activation. [PDF]

Lasers Med Sci
Honório S, Barbosa Carvalho P, Cristine de Souza Almeida R, Evangelista Alves Costa A, de Fátima Jacysyn J, Kiyomi Koike M, Russo Costa do Bomfim F, Frasson de Souza Montero E.   +7 more
europepmc   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Graft rejection across solid organ transplants: mechanisms, monitoring, and immunosuppressive therapeutics. [PDF]

Front Surg
Danso EA, Oduoye MO, Enuh WC, Wamiq U, Shuja H, Sawaira F, Fatima H, Tameez-Ud-Din S.   +7 more
europepmc   +1 more source

A Chemically Defined Four‐Component Self‐Adjuvanting Tn Vaccine Activating Mincle, FcγR, and CD206 for Enhanced Antitumor Immunity

Advanced Science, EarlyView.
A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming, Renyu Zhang, Xiaohui Li, Guiqi Li, Yu Niu, Deying Yang, Xiang Luo, Jun Liao, Zhongqiu Liu, Guochao Liao   +9 more
wiley   +1 more source