Results 191 to 200 of about 160,770 (374)

Rejuvenator effectiveness in reducing moisture and freeze/thaw damage on long-term performance of 20 % RAP asphalt mixes: An Australian case study

, 2020
Muhammad Aakif Ishaq, Filippo Giustozzi
openalex   +1 more source

Late-in-life treadmill-training rejuvenates autophagy, protein aggregate clearance, and function in mouse hearts [PDF]

, 2021
Jae Min Cho, Kellsey Ly, Caroline Ramous, Lauren Thompson, Michele Hansen, Maria Sara de Lima Coutinho Mattera, Karla Maria Pereira Pires, Maroua Ferhat, Kevin J. Whitehead, Kandis Carter, Márcio Buffolo, Rajeshwary Ghosh, Seul‐Ki Park, Sihem Boudina, J. David Symons   +14 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Clearance of senescent cells by navitoclax (ABT263) rejuvenates UHMWPE-induced osteolysis

, 2023
Weiping Su, Yihe Hu, Xiaolei Fan, Jie Xie   +3 more
openalex   +1 more source

Population dynamics, plasma cytokines and platelet centrifugation: Technical and sociodemographic aspects of ‘ovarian rejuvenation’ [PDF]

, 2023
E. Scott Sills, Seang Lin Tan
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Causes of water pollution : Ecological restoration and rejuvenation of rivers in context with India

, 2020
Hari Om Sharma
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

New Senolysis Approach via Antibody–Drug Conjugate Targeting of the Senescent Cell Marker Apolipoprotein D for Skin Rejuvenation [PDF]

, 2023
Kento Takaya, Toru Asou, Kazuo Kishi
openalex   +1 more source