Results 171 to 180 of about 20,124 (268)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Synergistic Effects of Endolift With Complementary Cosmetic Procedures: A Narrative Review and Comprehensive Approach. [PDF]

J Cosmet Dermatol
Nilforoushzadeh MA, Savoji PB, Fakhim T, Rafiei S, Mirbahari SN.   +4 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Radiographic Manifestation of Cosmetic Hand Rejuvenation With Calcium Hydroxyapatite. [PDF]

J Hand Surg Glob Online
Barré A, Al-Bayati A, Kluemper C.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

High-Intensity Focused Ultrasound for Facial Rejuvenation and Body Contouring: A Bibliometric Analysis of Efficacy and Safety Studies. [PDF]

Aesthet Surg J Open Forum
Kumar N, de Almeida GOO, Chen CM, Carruthers JDA.   +3 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targets. [PDF]

Mol Syst Biol
Camacho O, Koldobskiy MA, Reddy P, Oak A, Sun Y, Sherman K, Izpisua Belmonte JC, Feinberg AP.   +7 more
europepmc   +1 more source