Results 61 to 70 of about 19,260 (264)

Age, Depth, and Residual Depth Anomalies in the North Pacific: Implications for Thermal Models of the Lithosphere and Upper Mantle [PDF]

, 1986
We present an empirical basement depth versus age relation for the North Pacific Ocean, based on the statistical treatment of an ocean-wide gridded data set.
Renkin, Miriam K., Sclater, John G.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Investigations on microstructural and mechanical properties of long-term thermally exposed superalloy Mar-M247 after rejuvenation heat treatment

Journal of Materials Research and Technology
Mar-M247 is a polycrystalline nickel-based superalloy utilized for blades in heavy-duty gas turbines. However, the microstructure degradation of the alloy during long-term aging includes coarsening of the γ′ phase and precipitation of TCP phase, which ...
Song Wu, Lexin Yang, Yubing Pei, Fenling Wang, Changshuai Wang, Chao Luo, Bin Zhou, Xiufang Gong   +7 more
doaj   +1 more source

Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production [PDF]

, 2018
The ErbB2 blocker trastuzumab improves survival in oncologic patients, but can cause cardiotoxicity. The late Na+ current inhibitor ranolazine has been shown to counter experimental HF, including doxorubicin cardiotoxicity (a condition characterized by ...
Carlo G. Tocchetti, Carlo Maurea, Carmela Coppola, Chiara D'Avino, Chiara D'Avino, Claudia De Lorenzo, Claudia De Lorenzo, Claudio Arra, Danilo Fiore, Domenica Rea, Fabio Di Lisa, Gennaro Riccio, Gerolama Condorelli, Giovanna Piscopo, Michele Russo, Nicola Maurea, Salvatore Antonucci   +16 more
core   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Pharmacometabolomics reveals racial differences in response to atenolol treatment. [PDF]

, 2013
Antihypertensive drugs are among the most commonly prescribed drugs for chronic disease worldwide. The response to antihypertensive drugs varies substantially between individuals and important factors such as race that contribute to this heterogeneity ...
Beitelshees, Amber L, Boyle, Stephen, Chapman, Arlene B, Churchill, Erik, Cooper-Dehoff, Rhonda M, Fiehn, Oliver, Frye, Reginald F, Gong, Yan, Johnson, Julie A, Kaddurah-Daouk, Rima, Pharmacometabolomics Research Network, Wikoff, William R, Zhu, Hongjie   +12 more
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Thermomechanical processing of metallic glasses: Extending the range of the glassy state [PDF]

, 2016
© 2016 Macmillan Publishers Limited, part of Springer Nature. For crystalline metals, the science, technology and application of thermomechanical processing are established, but this is not true for glasses.
Concustell, A, Greer, AL, Sun, Y
core  

Thermoelectricity in Nanowires: A Generic Model

, 2010
By employing a Boltzmann transport equation and using an energy and size dependent relaxation time ($\tau$) approximation (RTA), we evaluate self-consistently the thermoelectric figure-of-merit $ZT$ of a quantum wire with rectangular cross-section.
Dresselhaus M S Heremans J P Rowe D M, Henry A S, Ioffe A F, Nolas G S, Shadyar Farhangfar   +4 more
core   +2 more sources

Skin responses to fractional photothermolysis [PDF]

, 2006
Background and Objective Fractional photothermolysis (FP) is a new concept using arrays of microscopic thermal damage patterns to stimulate a therapeutic response.
Anderson, Rox, Laubach, Hans-Joachim, Tannous, Zeina   +2 more
core   +1 more source