Results 81 to 90 of about 19,335 (278)

Dependence of structures and performances of soft-magnetic FeCo-based metal glasses on cryogenic treatments

Journal of Materials Research and Technology
The amorphous structures, thermal stability, soft-magnetic properties and microhardness have been explored for quaternary quenched (Fe0.8Co0.2)75B21Ta4 (Fe0.8) and (Fe0.5Co0.5)75B21Ta4 (Fe0.5) metallic glasses (MGs) after deep (77 K), moderate (173 K ...
Xin Zhang, Zongqi Xiao, Xingyu Zhou, Guoqiang Liu, Li Cai, Qikun Huang, Eugen Axinte, Guorong Zhou, Degang Zhao, Yan Wang   +9 more
doaj   +1 more source

The Effects of Various Conditions of Short-Term Rejuvenation Heat Treatment on Room-Temperature Mechanical Properties of Thermally Aged P92 Boiler Steel. [PDF]

Materials (Basel), 2021
Falat L, Čiripová L, Homolová V, Džupon M, Džunda R, Kovaľ K.   +5 more
europepmc   +1 more source

Infrared laser pulse triggers increased singlet oxygen production in tumour cells [PDF]

, 2013
Photodynamic therapy (PDT) is a technique developed to treat the ever-increasing global incidence of cancer. This technique utilises singlet oxygen (1O2) generation via a laser excited photosensitiser (PS) to kill cancer cells.
Goltsov, Alexey, Pourreyron, C., Rafailov, E. U., Sokolovski, S. G., South, A. P., Zolotovskaya, S. A.   +5 more
core   +4 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Non-linear susceptibility in glassy systems: a probe for cooperative dynamical length scales

, 2005
We argue that for generic systems close to a critical point, an extended Fluctuation-Dissipation relation connects the low frequency non-linear (cubic) susceptibility to the four-point correlation function.
A. Zippelius, C. Donati, D. Kivelson, E. Vincent, G. J. M. Koper, Giulio Biroli, H. Rieger, J. Cardy, J. P. Bouchaud, J. P. Bouchaud, J.-P. Bouchaud, Jean-Philippe Bouchaud, L. Berthier, L. Cugliandolo, M. Mézard, P. G. Debenedetti, S. Franz, T. Komori, W. Götze, W. Kob   +19 more
core   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source