Results 101 to 110 of about 216,694 (240)

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Metabolic pathways as possible therapeutic targets for progressive multiple sclerosis

Neural Regeneration Research, 2017
Unlike relapsing remitting multiple sclerosis, there are very few therapeutic options for patients with progressive forms of multiple sclerosis. While immune mechanisms are key participants in the pathogenesis of relapsing remitting multiple sclerosis ...
Rebecca M Heidker, Mitchell R Emerson, Steven M LeVine   +2 more
doaj   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Evaluation of Serum Auto Antibodies in Multiple Sclerosis Patients: A Case Control Study

International Clinical Neuroscience Journal, 2017
Background and Purpose: Multiple sclerosis (MS) is believed to be an immune-mediated disorder that develops from an interaction of the individual’s genetic and as yet unidentified environmental causes.
Sadegh Izadi, Saeede Khoshniat
doaj   +1 more source

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the management practices of Infantile Epileptic Spasms Syndrome (IESS) across tertiary pediatric hospitals in the United States using a survey‐based approach. Methods A 21‐question survey focused on management setting, work‐up, follow‐up and treatment was created and sent to 45 member institutions of the Pediatric ...
Akshat Katyayan, Christina Briscoe, Sonam Bhalla, Sonal Bhatia, Gozde Erdemir, Chellamani Harini, Senyene E. Hunter, John R. Mytinger, Duyu Nie, Archana Pasupuleti, Shital H. Patel, Debopam Samanta, Amanda Sandoval Karamian, Avantika Singh, Deepa Sirsi, Danielle S. Takacs, Shaun A. Hussain   +16 more
wiley   +1 more source

Impact of vigabatrin on risk of relapse of infantile spasms

Epilepsia Open, EarlyView.
Abstract Objective Vigabatrin is an effective treatment for infantile epileptic spasms syndrome (IESS), but relapse remains a clinical challenge. The ideal dose and duration of treatment after response are unknown. We set out to identify treatment‐related predictors of IESS relapse after initial vigabatrin response. Methods We conducted a retrospective
Yaretson I. Carmenate, Hayoung E. Ahn, Haley R. Peters, Hiroki Nariai, Rajsekar R. Rajaraman, Shaun A. Hussain   +5 more
wiley   +1 more source

Soluble CD163 Levels Correlate with EDSS in Female Patients with Relapsing–Remitting Multiple Sclerosis Undergoing Teriflunomide Treatment

BioMed
Background: multiple sclerosis (MS) presentation varies depending on the location and severity of the lesions affecting different areas of the spinal cord and brain.
Mario Jerčić, Maja Rogić Vidaković, Anita Markotić, Nikolina Režić Mužinić   +3 more
doaj   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

A Generalized Approach to Solving Deep Learning‐Based Quantitative Susceptibility Mapping and Quantitative Blood Oxygen Level Dependent Magnitude (QSM + qBOLD or QQ) for Oxygen Extraction Fraction (OEF) Mapping Across Diverse Acquisition Schemes

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose QQ, a recently proposed oxygen extraction fraction (OEF) mapping technique combining quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent (qBOLD) (QSM + qBOLD = QQ), generates OEF maps noninvasively from a single routine MRI sequence, without requiring vascular challenges used in other OEF approaches.
Tian Qiu, Ada Ally, Arpita Misra, Gloria C. Chiang, Thanh D. Nguyen, Susan A. Gauthier, Shun Zhang, Yi Wang, Junghun Cho   +8 more
wiley   +1 more source

1D Pre‐Acquisition Navigator Correcting Respiratory‐Induced Field Fluctuations in Multi‐Echo Gradient‐Echo Imaging of the Thoracic Spinal Cord

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose In the spinal cord (SC), multi‐echo gradient echo (ME‐GRE) increases gray (GM) and white matter (WM) contrast and improves sensitivity to lesions in people with multiple sclerosis (pwMS). However, SC ME‐GRE is susceptible to breathing‐induced field fluctuations, causing ghosting artifacts and signal loss.
Alicia E. Cronin, Alexandre D'Astous, Nathan Williams, Antoine Guénette, Aimee Salakhov, Seth Stubblefield, Colin D. McKnight, Lipika Narisetti, Subramaniam Sriram, Seth A. Smith, Ryan K. Robison, Guillaume Gilbert, Julien Cohen‐Adad, Kristin P. O'Grady   +13 more
wiley   +1 more source