Results 151 to 160 of about 216,694 (240)

H Syndrome Associated With Pure Red Cell Aplasia, Rosai–Dorfman Disease, and Sensorineural Hearing Loss: Phenotypic Variability in Three Children With the Same SLC29A3 Mutation

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT H syndrome is a rare autosomal recessive disorder caused by mutations in the SLC29A3 gene. We report three pediatric patients with a homozygous c.1309G>A (p.Gly437Arg) mutation presenting with distinct phenotypic variations. These cases expand the clinical spectrum and emphasize the importance of early genetic diagnosis and family counseling.
Mohammad Najajrah, Hadeel I. Bouzia, Nermin K. Darawi, Fatima S. Hajjaj, Nour H. Moosa, Noor M. Awad   +5 more
wiley   +1 more source

Investigating Depression and MRI Associations in Middle Eastern Relapsing-Remitting Multiple Sclerosis. [PDF]

J Biomed Phys Eng
Pishdad P, Zeinali-Rafsanjani B, Poursadeghfard M, Kalaee M, Ostovarfar J, Salehi A.   +5 more
europepmc   +1 more source

Chronic Recurrent Multifocal Osteomyelitis in a Pediatric Patient: An Uncommon Case With Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare autoinflammatory bone disorder that primarily affects children and adolescents. It is characterized by recurrent episodes of bone pain with sterile inflammatory lesions, often resembling infection or malignancy.
Dosti Regmi, Madhur Bhattarai, Sujata Bhandari, Saurav Jha, Akriti Baral   +4 more
wiley   +1 more source

Cost-Effectiveness of Dimethyl Fumarate Versus Teriflunomide in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS) in Iran. [PDF]

Health Sci Rep
Poursadeghfard M, Farjah Y, Rezaee M, Momtahan N, Morowvat MH, Gholami A, Keshavarz K.   +6 more
europepmc   +1 more source

The cGAS–STING Pathway Drives Astrocyte‐Mediated Demyelination in Multiple Sclerosis Through Clusterin Secretion

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
In multiple sclerosis, astrocytes detect extracellular DNA via the cGAS–STING pathway, triggering Clusterin secretion that induces oligodendrocyte apoptosis and demyelination. Pharmacological STING inhibition with H‐151 suppresses this neurotoxic cascade, preserves myelin integrity, and ameliorates clinical disability in experimental autoimmune ...
Shengfei Hu, Xia Xiao, Xi Cheng, Yiying Huang, Tingting Cui, Shishi Shen, Chunping Cui, Li Xiao, Hanzhang Tan, Wei Qiu, Yipeng Zhao, Rui Li   +11 more
wiley   +1 more source

Preliminary Psychometric Evaluation of the Romanian Version of the Hospital Anxiety and Depression Scale in Relapsing-Remitting Multiple Sclerosis. [PDF]

J Clin Med
Böckels L, Lisnic V, Alexa D, Belenciuc A, Crețu RA, Ropot D, Bîlcu RV, Cuciureanu DI.   +7 more
europepmc   +1 more source

Resolution of Paraneoplastic Cutaneous Angioendotheliomatosis After CAR T‐Cell Therapy in TP53‐Deleted CLL: A Case Report

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Cutaneous manifestations of chronic lymphocytic leukemia (CLL) are heterogeneous and may result from leukemic infiltration, secondary malignancies, infectious complications, or reactive inflammatory processes. Reactive angioendotheliomatosis (RAE) is a rare vascular proliferation that has only infrequently been reported in association with ...
Feras Alfraih, Mostafa F. Mohammed Saleh, David Li, Razan Mohty, Mohamed Kharfan‐Dabaja   +4 more
wiley   +1 more source

Efficacy and safety of monoclonal antibodies in the treatment of relapsing remitting multiple sclerosis: a systematic review. [PDF]

J Neurol
Avedillo-Salas A, Martínez LB, Fanlo-Villacampa A, Vicente-Romero J.   +3 more
europepmc   +1 more source

Standard Model Imaging in the Brain and Spinal Cord of MS Patients: Initial Assessment and Comparison to Diffusion Tensor Imaging

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
DTI and SMIfw diffusion models applied in persons with multiple sclerosis revealed region‐specific sensitivity to microstructural injury, but performance differed by anatomical region. SMIfw neurite density fraction demonstrated high sensitivity and reliability in both the brain and spinal cord, whereas DTI measures such as fractional anisotropy and ...
Atlee Witt, Alicia E. Cronin, Bailey Busher, Isabella Stuart, Grace Sweeney, Kristin P. O'Grady, Seth A. Smith, Samantha By, Kurt Schilling   +8 more
wiley   +1 more source

Central Vein Sign and Paramagnetic Rim Lesions in Patients with Relapsing-Remitting Multiple Sclerosis: An Assessment of Prevalence and Anatomical Location. [PDF]

Neurol Int
Jansone MN, Zdanovskis N, Polunosika E, Pastare D, Karelis G.   +4 more
europepmc   +1 more source