Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity [PDF]
, 2009 Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates.
AG Barbour +59 more
core +7 more sources
Tick-Born Relapsing Fever and Genespecies Diversity of Borrelia: Current Status
Эпидемиология и вакцинопрофилактика, 2022 Relevance. Tick-borne relapsing fevers caused by Borrelia species pathogenic for humans are not well understood. Aim of this review is to assess the genetic diversity of Borrelia with special attention to the relapsing fever group and phylogenetically ...
T. A. Chekanova, I. N. Manzeniuk
doaj +1 more source
Multiple and Diverse vsp and vlp Sequences in Borrelia miyamotoi, a Hard Tick-Borne Zoonotic Pathogen. [PDF]
PLoS ONE, 2016 Based on chromosome sequences, the human pathogen Borrelia miyamotoi phylogenetically clusters with species that cause relapsing fever. But atypically for relapsing fever agents, B. miyamotoi is transmitted not by soft ticks but by hard ticks, which also
Alan G Barbour
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Relapsing Fever–Like Spirochetes Infecting European Vector Tick of Lyme Disease Agent
Emerging Infectious Diseases, 2003 To determine whether relapsing fever–like spirochetes associated with hard ticks may infect Ixodes ricinus ticks in central Europe, we screened questing ticks for 16S rDNA similar to that of Asian and American relapsing fever–like spirochetes.
Dania Richter +2 more
doaj +1 more source
"Candidatus Borrelia kalaharica" Detected from a Febrile Traveller Returning to Germany from Vacation in Southern Africa. [PDF]
PLoS Neglected Tropical Diseases, 2016 A 26 year-old female patient presented to the Tropical Medicine outpatient unit of the Ludwig Maximilians-University in Munich with febrile illness after returning from Southern Africa, where she contracted a bite by a large mite-like arthropod, most ...
Volker Fingerle +8 more
doaj +1 more source
Possibilities for Relapsing Fever Reemergence
Emerging Infectious Diseases, 2006 Relapsing fever Borrelia infections have attracted little attention in recent years; however, where endemic, these infections still result in considerable illness and death. Despite the marked antimicrobial drug susceptibility of these organisms, therapy
Sally J. Cutler
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Pathogenic New World Relapsing Fever Borrelia in a Myotis Bat, Eastern China, 2015
Emerging Infectious Diseases, 2020 We identified Candidatus Borrelia fainii, a human pathogenic bacterium causing New World relapsing fever in a Myotis bat in eastern China. This finding expands knowledge about the geographic distribution of Borrelia spp.
Hui-Ju Han +9 more
doaj +1 more source
Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi [PDF]
, 2017 The emerging pathogen, Borrelia miyamotoi, is a relapsing fever spirochete vectored by the same species of Ixodes ticks that carry the causative agents of Lyme disease in the US, Europe, and Asia. Symptoms caused by infection with B.
Brandee L. Stone, Catherine A. Brissette
core +1 more source
Typing African Relapsing Fever Spirochetes
Emerging Infectious Diseases, 2005 Relapsing fever Borrelia spp. challenge microbiologic typing because they possess segmented genomes that maintain essential genes on large linear plasmids. Antigenic variation further complicates typing.
Julie Christine Scott +2 more
doaj +1 more source
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. [PDF]
, 2012 Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors.
Alessandro eSette +8 more
core +1 more source