Results 41 to 50 of about 49,422 (318)
Advanced Science, EarlyView.A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun +23 more
wiley +1 more source
Identifying Relapsing Fever Borrelia, Senegal
Emerging Infectious Diseases, 2005 We describe a nested polymerase chain reaction for the identification of Borrelia species from serum of patients with unidentified fevers. This technique, based on single nucleotide polymorphisms of the 16S ribosomal RNA gene, was used to test blood ...
Hamoud Brahim +4 more
doaj +1 more source
First detection of Borrelia miyamotoi in Ixodes ricinus ticks from northern Italy. [PDF]
, 2018 Borrelia miyamotoi is a spirochete transmitted by several ixodid tick species. It causes a relapsing fever in humans and is currently considered as an emerging pathogen. In Europe, B. miyamotoi seems to occur at low prevalence in Ixodes ricinus ticks but
Capelli, Gioia +8 more
core +3 more sources
Advanced Science, EarlyView.Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun +14 more
wiley +1 more source
Case Report and Genetic Sequence Analysis of Candidatus Borrelia kalaharica, Southern Africa
Emerging Infectious Diseases, 2018 Tickborne relapsing fever caused by Borrelia species is rarely reported in travelers returning from Africa. We report a case of a 71-year-old woman who sought treatment at University Medical Center in Freiburg, Germany, in 2015 with recurrent fever after
Katarina Stete +6 more
doaj +1 more source
Relapsing polychondritis [PDF]
, 1998 PURPOSE: This article describes a clinically-diagnosed case of relapsing polychondritis (RP), attended at the Hospital São Paulo, and presents a literature review of the subject.
Andrade Junior, Ary de +3 more
core +2 more sources
Randomized Comparison of Cardiotoxicity With 60 Versus 90 mg Daunorubicin in AML Induction Therapy
American Journal of Hematology, EarlyView.Early cardiac biomarker monitoring in AML induction therapy showed significantly higher hsTnT levels after daunorubicin 90 mg/m2 compared with 60 mg/m2, indicating a dose‐dependent early myocardial effect. ABSTRACT Anthracyclines are an essential component of induction therapy for acute myeloid leukemia (AML), but their optimal dosing and the ...
Stefan Markus Dendorfer +44 more
wiley +1 more source
Iranian Journal of Public Health, 1996 In order to study the distribution of Argasidae family ticks and the role of O.tholozani in transmitting the relapsing fever agent in rural areas of central province, an investigation was carried out from June to November 1992.
M. Salimi +2 more
doaj
Annals of Neurology, EarlyView.Objective To assess real‐world effectiveness of switching disease‐modifying therapy (DMT) in pediatric multiple sclerosis (MS) and clinically isolated syndrome (CIS) initially treated with platform injectables on disease activity. Methods Of 2615 pediatric‐onset demyelinating disease patients at 12 clinics in the United States (US) Network of Pediatric
Aaron W. Abrams +27 more
wiley +1 more source
Borrelia hispanica Relapsing Fever, Morocco
Emerging Infectious Diseases, 2009 We found that 20.5% of patients with an unexplained fever in northwestern Morocco had tick-borne relapsing fever. Molecular detection specific for the 16S rRNA gene identified Borrelia hispanica.
M’hammed Sarih +8 more
doaj +1 more source