Results 51 to 60 of about 11,136,976 (333)

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider   +14 more
wiley   +1 more source

Navigating Autonomy, Competence, and Relatedness: Insights from Middle Managers in Norway

open access: yesAdministrative Sciences
Middle managers play a pivotal role in bridging the gap between senior leadership and employees, often navigating competing demands and pressures. This study investigates experiences of autonomy, competence, and relatedness among middle managers serving ...
Kristin Severinsen Spieler
doaj   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

open access: yesAdvanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Exploring Basic Psychological Need Satisfaction and Relationship Quality as Protective Factors of Mental Well-Being During the COVID-19 Pandemic

open access: yesEurope's Journal of Psychology
COVID-19’s global impact on mental health has been profound. To better understand factors that mitigate effects of stress, particularly during quarantine periods, this study examined roles of basic psychological need satisfaction and relationship quality
Barbara Horvát   +4 more
doaj   +1 more source

Relatedness disequilibrium regression estimates heritability without environmental bias

open access: yesNature Genetics, 2018
Heritability measures the proportion of trait variation that is due to genetic inheritance. Measurement of heritability is important in the nature-versus-nurture debate.
Alexander I. Young   +9 more
semanticscholar   +1 more source

On the Relatedness and Nestedness of Constraints [PDF]

open access: yesSports Medicine - Open, 2019
The purpose of this opinion paper is providing a platform for explaining and discussing the relatedness and nestedness of constraints on the basis of four claims: (a) task constraints are distributed between the person and the environment and hence are relational variables, (b) being relational, task constraints are also emergent properties of the ...
Balagué Serre, Natàlia   +4 more
openaire   +4 more sources

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

open access: yesAdvanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li   +23 more
wiley   +1 more source

Reproductive performance links to fine-scale spatial patterns of female grey seal relatedness [PDF]

open access: yes, 2001
Fine–scale spatial patterns of female relatedness throughout the established grey seal breeding colony of North Rona, Scotland, were investigated by accurate mapping and spatially explicit analyses of a large sample (n=262) of mothers using variation at ...
P. P. Pomeroy   +11 more
core   +1 more source

From microsatellites to single nucleotide polymorphisms for the genetic monitoring of a critically endangered sturgeon

open access: yesEcology and Evolution, 2019
The use of genetic information is crucial in conservation programs for the establishment of breeding plans and for the evaluation of restocking success.
Séverine Roques   +4 more
doaj   +1 more source

The significance of relatedness in healthcare [PDF]

open access: yesMedicine, Health Care and Philosophy, 2014
The tradition of anthropological medicine in the first half of the twentieth century regarded medicine first of all as a relational activity. Its aim was to develop medicine as a science of human beings, building on the ideas of phenomenology, existentialism and philosophical anthropology (Ten Have 1995). Rather than applying the findings of scientific
Henk, ten Have, Bert, Gordijn
openaire   +2 more sources

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