Results 141 to 150 of about 106,391,986 (305)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Scaling up Pattern Induction for Web Relation Extraction through Frequent Itemset Mining [PDF]
, 2008 Blohm S, Cimiano P. Scaling up Pattern Induction for Web Relation Extraction through Frequent Itemset Mining. In: Adrian B, Neumann G, Troussov A, Popov B, eds.
Troussov, Alexander +5 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Patient's Attitude towards the Faculty of Medicine Siriraj Hospital's Information Services
Siriraj Medical Journal, 2004 Objectives : To study an association between patients' demographics and their attitudes including their attitudes towards the Faculty of Medicine Siriraj Hospital' s Information Services.
Panee Charoensethamaha
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Report of The First Regional Seminar on Industrial Relations in The Asean Region
, 2010 v.188 hal.;ill.;30 ...
Industrial Relation Project
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Note on the constraint on modified energy-momentum relation
, 2006 Quantum gravity can modify the usual energy-momentum dispersion relation. We provide evidence for the argument that the modified dispersion relation is constrained by the black hole thermodynamics, for consistency of quantum ...
Shen You-Gen, Li Xiang
core