Results 191 to 200 of about 5,797,629 (324)

Relation Extraction Using Semantic Information

Computational Linguistics, 2023
Jian Xu, Qin Lu, Minglei Li
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Knowledge enhancement and full utilization of document information for document-level biomedical relation extraction. [PDF]

Sci Rep
Chen X, He L, Liu Y.
europepmc   +1 more source

Towards generic relation extraction

, 2009
A vast amount of usable electronic data is in the form of unstructured text. The relation extraction task aims to identify useful information in text (e.g., PersonW works for OrganisationX, GeneY encodes ProteinZ) and recode it in a format such as a relational database that can be more effectively used for querying and automated reasoning.
openaire   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Knowledge-augmented pre-trained language models for biomedical relation extraction. [PDF]

BMC Bioinformatics
Sänger M, Leser U.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Using large language models for temporal relation extraction from pediatric clinical reports. [PDF]

JAMIA Open
Andrew JJ, Potier J, Garcelon N, Burgun A, Vincent M.   +4 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Exploring transformer models: Fine-tuning VS inference on relation extraction from biomedical texts. [PDF]

Comput Struct Biotechnol J
El Janah H, Nachid-Idrissi Y, Sarrouti M, Najah S.   +3 more
europepmc   +1 more source