Results 251 to 260 of about 745,152 (307)

Integrating deep learning architectures for enhanced biomedical relation extraction: a pipeline approach. [PDF]

Database (Oxford)
Sarol MJ, Hong G, Guerra E, Kilicoglu H.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

DiffFSRE: Diffusion-Enhanced Prototypical Network for Few-Shot Relation Extraction. [PDF]

Entropy (Basel)
Chen Y, Shi B.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimized biomedical entity relation extraction method with data augmentation and classification using GPT-4 and Gemini. [PDF]

Database (Oxford)
Phan CP, Phan B, Chiang JH.
europepmc   +1 more source

Research on joint model relation extraction method based on entity mapping. [PDF]

PLoS One
Tang H, Zhu D, Tang W, Wang S, Wang Y, Wang L.   +5 more
europepmc   +1 more source

FSN: Joint Entity and Relation Extraction Based on Filter Separator Network. [PDF]

Entropy (Basel)
Dai Q, Yang W, Wei F, He L, Liao Y.
europepmc   +1 more source

Correction to: The overview of the BioRED (Biomedical Relation Extraction Dataset) track at BioCreative VIII. [PDF]

Database (Oxford)
europepmc   +1 more source

Document-level biomedical relation extraction via hierarchical tree graph and relation segmentation module. [PDF]

Bioinformatics
Yuan J, Zhang F, Qiu Y, Lin H, Zhang Y.
europepmc   +1 more source