Results 91 to 100 of about 17,457,237 (334)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Mankind at the Crossroads: Civilizational Shift or Self-destruction

open access: yesCadmus, 2019
Society has two parallel lines of development—the Course of History and the Spiral of Social Evolution. Development is determined bilaterally by objective and subjective factors.
Dimitar Tchurovsky
doaj  

Contribution of the alternative model for DSM-5 personality disorders to relationship satisfaction

open access: yesFrontiers in Psychiatry
IntroductionPersonality is a central factor associated with relationship discord, conflicts, and separation, as well as with dyadic adjustment and relationship stability. The Alternative Model for Personality Disorders (AMPD) of the DSM-5 offers a hybrid
Claudia Savard   +15 more
doaj   +1 more source

Relationship based Entity Recommendation System [PDF]

open access: yes, 2015
With the increase in usage of the internet as a place to search for information, the importance of the level of relevance of the results returned by search engines have increased by many folds in recent years.
Verma, Rakhi Poonam
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Financial strain among West-Javanese parents: its association with marital satisfaction and quality of life, and the role of dyadic coping

open access: yesFrontiers in Psychology
In the past decade, the concept of dyadic coping as a buffer against stress in romantic relationships has received much attention in Western countries, but it has rarely been studied in non-Western countries and among parents with school-aged children ...
Langgersari Elsari Novianti   +5 more
doaj   +1 more source

Cacao’s Relationship with Mesoamerican Society [PDF]

open access: yes, 2013
We know what we eat, but do we eat what we know? Our diet extends far beyond nutrients and food availability—we imbue food with cultural significance. The meaning and use of a particular food is subject to change over time, but the fact that it holds a ...
Christopher, Hillary
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Fiduciary relationships

open access: yesCurrent Sociology
Although fiduciary relationships have a long tradition in Hammurabic, Jewish or Islamic codifications, they were especially conceived and instituted by Roman civil (private) law to normatively address asymmetrical interindividual relationships in which a settlor or beneficiary has an interest in the performance of a certain action, but does not have ...
openaire   +2 more sources

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