Results 61 to 70 of about 4,596,905 (247)
A Closed-Loop Toolchain for Neural Network Simulations of Learning Autonomous Agents
Frontiers in Computational Neuroscience, 2019 Neural network simulation is an important tool for generating and evaluating hypotheses on the structure, dynamics, and function of neural circuits. For scientific questions addressing organisms operating autonomously in their environments, in particular
Jakob Jordan +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Nutrition and Food Sciences Research, 2016 Background and Objectives: The addition of plasticizers (mainly phthalates and adipates) makes plastic flexible and popular for packaging, storing and preserving food, water, and so on.
Mohammad Faraji, Mahnaz Adeli
doaj
Ensuring Stable Operation of Wind Farms Connected to Distribution Networks
Applied SciencesWind farms with type IV wind turbines from various manufacturers are being massively put into operation. These wind turbines comply with the requirements of the grid codes of the countries where they are designed and/or manufactured, but do not factor in
Pavel Ilyushin +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Jurnal Keperawatan Klinis dan Komunitas (Clinical and Community Nursing Journal), 2019 Background: Pre hospital patient management is a significant part to decrease early and late death. Head injury in traffic accident victims may increase intracranial pressure which leads to decrease victim’s consciousness.
Yuninda Kurniawati, Sutono Sutono
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Psychologica Belgica, 2017 We test two assumptions of the generalized prejudice literature. First, that the structure of generalized prejudice (i.e. how prejudices are interrelated) is dependent on the intergroup context.
Cecil Meeusen +2 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source