Results 71 to 80 of about 8,589,275 (309)

Sex-Specific Vulnerability of Fish to Dredging in the Mediterranean Coastal Lagoon (Lake Manzala, Egypt)

open access: yesAquatic Sciences and Engineering
Lagoon dredging disrupts aquatic ecosystems and fish populations. A study in Lake Manzala, Egypt, assessed these impacts by analyzing 2616 fish across ten species.
Azza El-ganainy   +2 more
doaj   +1 more source

Length-weight and length-length relationships and condition factor of Alburnus chalcoides (Güldenstädt, 1772) populations from rivers of the southern Caspian Sea [PDF]

open access: yesبوم‌شناسی آبزیان, 2021
In This study, the length-weight and fork-total length relationships, growth pattern and condition factor of Alburnus chalcoides, was estimated during 2006-2007. A total of 170 specimens were collected from the Chelvand, Khalehsara, Siahdarvishan, Sefid,
Atta Mouludi-Saleh   +2 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

ARM'S-LENGTH RELATIONSHIPS WITHOUT MORAL HAZARD [PDF]

open access: yesJournal of the European Economic Association, 2010
I show that cutting the flow of information between a principal and an agent can increase the power of the incentives of the agent to reveal private information. (JEL: D23, D82, D86, L20)
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Is telomere length a biomarker for aging: cross-sectional evidence from the west of Scotland? [PDF]

open access: yes, 2012
Background <p> The search for biomarkers of aging (BoAs) has been largely unsuccessful to-date and there is widespread skepticism about the prospects of finding any that satisfy the criteria developed by the American Federation of Aging Research ...
Batty, G.D.   +46 more
core   +1 more source

Rat superficial masseter operates at long lengths during biting

open access: yesScientific Reports
The operating length ranges of mammalian jaw muscles have been estimated using twitch contractions or force measurements at the bite point, prompting a consensus that jaw muscles operate at short lengths on their force-length (FL) curve.
Nicolai Konow   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Length-weight and length-length relationships, Relative condition factor and Fulton’s condition factor of Five Cyprinid species in Anzali wetland, southwest of the Caspian Sea

open access: yesCaspian Journal of Environmental Sciences, 2012
This study was conducted to determine length-weight and length-length relationships, relative condition factor (Krel) and Fulton’s condition factor (K) for five species including Scardinius erythrophtalmus, Carassius auratus gibelio, Cyprinus carpio ...
Moradinasab, Gh.   +4 more
doaj  

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