Results 11 to 20 of about 1,495,455 (254)
CYCLOSPORINE—RELATIONSHIP OF SIDE EFFECTS TO MODE OF ACTION
Although cyclosporine has high specificity for the immune system, immunosuppressive therapy with CsA is often complicated by nephrotoxicity. The main morphologic targets of CsA nephrotoxicity include the tubular epithelial and endothelial cells. These cells were investigated in vitro.
B, Ryffel +5 more
openaire +3 more sources
Doping Dependence of Bilayer Resonant Spin Excitations in $\bf (Y,Ca)Ba_2Cu_3O_{6+x}$
Resonant magnetic modes with odd and even symmetries were studied by inelastic neutron scattering experiments in the bilayer high-$T_c$ superconductor $\rm Y_{1-x}Ca_{x}Ba_2Cu_3O_{6+y}$ over a wide doping range.
A. Ivanov +10 more
core +1 more source
The fractality of the relaxation modes in deterministic reaction-diffusion systems
In chaotic reaction-diffusion systems with two degrees of freedom, the modes governing the exponential relaxation to the thermodynamic equilibrium present a fractal structure which can be characterized by a Hausdorff dimension. For long wavelength modes,
Barra +22 more
core +1 more source
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee +9 more
wiley +1 more source
Solitons in a six-dimensional super Yang-Mills-tensor system and noncritical strings [PDF]
In this letter we study a coupled system of six-dimensional N=1 tensor and super Yang-Mills multiplets. We identify some of the solitonic states of this system which exhibit stringy behaviour in six dimensions. A discussion of the supercharges and energy
Nair, V. P., Randjbar-Daemi, S.
core +2 more sources
Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek +13 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Frog tendon structure and its relationship with locomotor modes [PDF]
AbstractTendon collagen fibrils are the basic force‐transmitting units of the tendon. Yet, surprisingly little is known about the diversity in tendon anatomy and ultrastructure, and the possible relationships between this diversity and locomotor modes utilized.
Virginia Abdala +4 more
openaire +3 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source

