Results 121 to 130 of about 4,295,535 (295)

Relative Density-Based Intuitionistic Fuzzy SVM for Class Imbalance Learning. [PDF]

Entropy (Basel), 2022
Fu C, Zhou S, Zhang D, Chen L.
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Laser powder bed fusion process optimization of CoCrMo alloy assisted by machine-learning

Journal of Materials Research and Technology
Gaussian process regression (GPR) model of machine learning method was employed to identify the optimal process window for high-performance CoCrMo alloy in laser powder bed fusion (LPBF), considering density (≥99%) and surface roughness (≤7 μm) as key ...
Haoqing Li, Bao Song, Yizhen Wang, Jingrui Zhang, Weihong Zhao, Xiaoying Fang   +5 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Pore Water Pressure Generation and Energy Dissipation Characteristics of Sand–Gravel Mixtures Subjected to Cyclic Loading

Geotechnics
At least 32 case histories have shown that liquefaction can occur in gravelly soils (both natural deposits and manmade reclamations) during severe earthquakes, causing large ground deformations and severe damage to civil infrastructures.
Abilash Pokhrel, Gabriele Chiaro
doaj   +1 more source

Experimental Investigation of the Mechanical Properties of the Sand-Concrete Pile Interface Considering Roughness and Relative Density. [PDF]

Materials (Basel), 2022
Chen C, Yang Q, Leng W, Dong J, Xu F, Wei L, Ruan B.   +6 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Correlations Between Inflammatory Cell Infiltration and Relative Density and the Boundary Manifestation of Pulmonary Non-Neoplastic Ground Glass Nodules. [PDF]

J Inflamm Res, 2023
Liu XL, Lv FJ, Fu BJ, Lin RY, Li WJ, Chu ZG.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Determination of Relative Density and Degree of Saturation in Mineral Soils Based on In Situ Tests. [PDF]

Materials (Basel), 2021
Rabarijoely S, Lech M, Bajda M.
europepmc   +1 more source