Results 201 to 210 of about 1,655,421 (263)

Research on Density Prediction of Laser Powder Bed Fusion Process Parameters for IN718 Nickel-Based Superalloy Based on Machine Learning. [PDF]

Materials (Basel)
Zhu L, Wang J, Song Z, Guo H, Li B, Liu Y.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Development and Physicochemical Stability of an Oral GS-441524 Suspension for Weight-Adjusted Treatment of Feline Infectious Peritonitis. [PDF]

Vet Med Sci
Wernli C, Streit U.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Accurate alpha-particle stopping power measurements in graphenic carbon foils and their application to high-precision, non-destructive areal density determination. [PDF]

Sci Rep
Botsiou K, Purushothaman S, Geissel H, Dickel T, Enders J, Haettner E, Morrissey DJ, Saifulin M, Scheidenberger C, Tomut M, Weick H, Zhao J.   +11 more
europepmc   +1 more source

Protection Management, Nurse Plants, and Diversity of Companion Species Influence Natural Regeneration of <i>Pinus gerardiana</i> in the Western Himalayan Pine Forests. [PDF]

Ecol Evol
Sultani Ahmadzai A, Ejtehadi H, Bashirzadeh M, Farzam M.   +3 more
europepmc   +1 more source

Comparative Torsional Properties via Numerical Simulation of Triply Periodic Minimal Surfaces (TPMS): Diamond, Gyroid and Primitive Structures. [PDF]

Polymers (Basel)
Skibar M, Susantyoko RA, Pervaiz S.
europepmc   +1 more source

Influence of cell culture parameters on oxygen diffusion and cell distribution in 3D-porous scaffolds for bone tissue engineering: finite element modeling and experimental verification. [PDF]

Med Biol Eng Comput
Saatchi A, Seddiqi H, Amoabediny G, Helder MN, Zandieh-Doulabi B, Klein-Nulend J.   +5 more
europepmc   +1 more source

Drivers and Consequences of Size Declines in Unicells. [PDF]

Ecol Lett
Marshall DJ, Cameron HE, Abe A, Leles SG, White CR, Delong J.   +5 more
europepmc   +1 more source