Results 141 to 150 of about 3,761,115 (301)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Functional Response (FR) and Relative Growth Rate (RGR) Do Not Show the Known Invasiveness of Lemna minuta (Kunth). [PDF]
PLoS One, 2016 Van Echelpoel W, Boets P, Goethals PL.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Does seed mass drive the differences in relative growth rate between growth forms? [PDF]
Proc Biol Sci, 2013 Houghton J, Thompson K, Rees M.
europepmc +1 more source
The effects of population aging on optimal redistributive taxes in an overlapping generations model [PDF]
The impact of population aging on the steady state solution to a Ordover-Phelps (1979) overlapping generations optimal nonlinear income tax problem with two types of workers and quasilinear-in-leisure preferences is investigated.
Brett, Craig
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Relative growth rate variation of evergreen and deciduous savanna tree species is driven by different traits. [PDF]
Ann Bot, 2014 Tomlinson KW +5 more
europepmc +1 more source
Economic and financial market consequences of ageing populations [PDF]
The implications of ageing populations over the coming decades at the global level will be significant in terms of not only a slowdown in the growth rate of output and living standards but also with regard to fiscal and financial market trends. Given the
Kieran Mc Morrow, Werner R�ger
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Response of insect relative growth rate to temperature and host-plant phenology: estimation and validation from field data. [PDF]
PLoS One, 2014 Ciss M +5 more
europepmc +1 more source