Results 161 to 170 of about 15,119,997 (287)

RELATIVE AGRICULTURAL PRICE CHANGES IN DIFFERENT TIME HORIZONS [PDF]

open access: yes
Using a monthly data covering from 1974:1 to 2002:12, this paper explores the linkage between changes in macroeconomic variables (real exchange rate and inflation rate) and changes in relative agricultural prices in different time horizons (1, 12, 24, 36,
Kim, MinKyoung, Koo, Won W., Cho, Guedae
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Exchange Rate Regimes and Pro-Poor Growth [PDF]

open access: yes
This paper extends the ongoing discussion on optimal exchange rate regimes to the issue of pro-poor growth. To analyze empirically the poverty effects of exchange rate regimes, we estimate the distribution effects of different exchange rate arrangements ...
Rolf Maier
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Interferencia entre Phaseolus vulgaris L. y Amaranthus dubius Mart.: Análisis de crecimiento funcional en un modelo de series de reemplazo

open access: yesBioagro
Amaranthus dubius es una maleza frecuente en los cultivos de Phaseolus vulgaris en los estados centrales y occidentales de Venezuela. Para evaluar el efecto de la interferencia sobre el crecimiento de ambas especies creciendo en diferentes proporciones ...
José Vicente Lazo, Jocelyne Ascencio
doaj  

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