Results 191 to 200 of about 5,714,491 (338)

Partitioning the Components of Relative Growth Rate: How Important Is Plant Size Variation?

open access: yesAmerican Naturalist, 2010
M. Rees   +5 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Thermal performance of <i>Wolffia globosa</i> under climate change: heatwaves impair population growth. [PDF]

open access: yesAoB Plants
Cuddington K   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interferencia entre Phaseolus vulgaris L. y Amaranthus dubius Mart.: Análisis de crecimiento funcional en un modelo de series de reemplazo

open access: yesBioagro
Amaranthus dubius es una maleza frecuente en los cultivos de Phaseolus vulgaris en los estados centrales y occidentales de Venezuela. Para evaluar el efecto de la interferencia sobre el crecimiento de ambas especies creciendo en diferentes proporciones ...
José Vicente Lazo, Jocelyne Ascencio
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A Classifier for Patient-Derived Colorectal Tumoroid Drug Sensitivity Using Confocal Imaging and Growth Rate Inhibition Metrics. [PDF]

open access: yesCancer Res Commun
Sakshaug BC   +12 more
europepmc   +1 more source

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