Results 191 to 200 of about 1,251,336 (263)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Response of <i>Atalantia buxifolia</i> to Salt Stress Based on Physiological and Transcriptome Analysis. [PDF]

Biology (Basel)
Yang Y, Hu W, Chen J, Qu J, Chen C, Wu C.   +5 more
europepmc   +1 more source

Genetic trends for kleiber ratio and relative growth rate from weaning to six months of age.

Asfaw Bisrat (22772723), Shanbel Besufkad (22772726), Aschalew Abebe (22772729), Shenkute Goshme (22772732), Ayele Abebe (6020900), Tesfaye Zewdie (22772735), Alemnew Areaya (22772738), Zeleke Tesema (17054687), Chekol Demis (22772741), Erdachew Yitagesu (22772744), Yeshitila Wondifra (22772747), Tadiwos Asfaw (22772750), Enyiew Alemnew (22772753), Solomon Gizaw (4391332), Tesfaye Getachew (4391326), Barbara Rischkowsky (3300732), Mourad Rekik (5127341), Berhanu Belay (13833594), Aynalem Haile (4391323)   +18 more
openalex   +1 more source

Appendix C. A summary of ANOVAs evaluating the effects of seed mass and light environment on seedling biomass and relative growth rate one year after emergence in species of Psychotria in greenhouse experiments 1 and 2.

, 2016
Horacio Paz, Miguel Martínez‐Ramos
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Effects of planting density and foliar fertilization on the phyllosphere microbial community of dual-purpose soybean. [PDF]

BMC Plant Biol
Xu Q, Huang M, Huang Q, Xiong P, Lu M, Deng C, Song Q, Meng Y, Wu D, Xu L.   +9 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Assessing the Chronic Effects of Dietary Aluminum on Fitness Traits, Acetylcholinesterase Activity and Locomotion in <i>Lymantria dispar</i> L. Larvae. [PDF]

Insects
Vlahović M, Matić D, Todorović D, Petković B, Ilijin L, Mrdaković M, Perić-Mataruga V.   +6 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Silencing of SlERF.F5 affects tolerance to drought, salt and low-temperature stresses in tomato. [PDF]

BMC Genomics
Chen Y, Liao X, Li W, Cheng X, Qi B, Gao J, Wan F.   +6 more
europepmc   +1 more source