Results 261 to 270 of about 5,714,491 (338)

Effects of sodium nitroprusside and salicylic acid applications on morphological, physiological and biochemical properties of Garnem (Prunus dulcis × Prunus persica) rootstock against alkaline stress under in vitro conditions. [PDF]

BMC Plant Biol
Şaşkın N, Ak BE, Eki̇nci̇ H, Sarioğlu A.   +3 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Morphological Diversity of <i>Epichloë sinensis</i> from <i>Festuca sinensis</i> Germplasm on the Qinghai-Tibet Plateau. [PDF]

J Fungi (Basel)
Liu J, Sun J, Zhao Y, Li Z, Zhang M, Cui L, Shen J, Luo Y, Gao Y, Zhou W, Chen T, Wang T, Du M, Liu W, Xia C, Hu T, Tian P.   +16 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Understanding the direct and indirect impacts of disease response phenotypes on chicken coccidiosis epidemiology: A modelling approach. [PDF]

PLoS One
Ithurbide M, Pinard van der Laan MH, Gao Y, Hulst AD, De Jong MCM, Doeschl-Wilson A.   +5 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Coordinated regulation of tomato sugar accumulation by relative humidity and field capacity through source-sink-transport balance. [PDF]

Front Plant Sci
Han W, Zhang X, Hao Y, Sun C, Lin X.
europepmc   +1 more source

Limits to the evolution of metabolic dependency in spatially structured microbial communities. [PDF]

iScience
Ramesh D, Fara E, Oschmann F, Ugolini GS, Stocker R, van Vliet S, Ackermann M, Schubert OT.   +7 more
europepmc   +1 more source