Results 101 to 110 of about 5,272,079 (317)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Environmental changes during secondary succession in a tropical dry forest in Mexico [PDF]
, 2011 Vegetation and environment change mutually during secondary succession, yet the idiosyncrasies of the vegetation effect on the understorey environment are poorly understood. To test whether the successional understorey environment changes predictably and
Bongers, F. +4 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Italian National Conference on Sensors, 2018 This paper presents a system capable of measuring temperature and relative humidity with polymer optical fiber (POF) sensors. The sensors are based on variations of the Young’s and shear moduli of the POF with variations in temperature and relative ...
A. Leal-Junior +3 more
semanticscholar +1 more source
GLOBE Cave Protocol Field Guide: Comparing Surface and Subterranean Environments [PDF]
, 2003 The GLOBE Cave Protocol Field Guide utilizes existing GLOBE protocols to explore an extreme environment. Caves provide an opportunity to utilize GLOBE protocols to investigate underground environments and compare them to surface environments. Outside the
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
TREND ANALYSIS OF RELATIVE HUMIDITY IN KHULNA OF BANGLADESH FROM HISTORICAL DATA [PDF]
Geological BehaviorBangladesh, despite having a subtropical climate, is characterized by dry winters and hot summers, ranks top among the most vulnerable countries to climate change.
Md. Sarwar Jahan
doaj +1 more source
The capability of capacitive sensors in the monitoring relative humidity in hypogeum environments [PDF]
, 2018 Hypogeum environments are characterized by high levels of relative humidity (RH). Most humidity sensors currently in use are based on the capacitive effect of the dielectric material to change according to water vapour uptake.
Caratelli, A, Frasca, F, Siani, Am
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source