Results 91 to 100 of about 5,272,079 (317)

Use of polyethylene glycol coatings for optical fibre humidity sensing [PDF]

open access: yes, 2008
Humidity induced change in the refractive index and thickness of the polyethylene glycol (PEG) coatings are in situ investigated for a range from 10 to 95%, using an optical waveguide spectroscopic technique.
B. D. Gupta   +31 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Evaluating Calibration Uncertainty and Response Time of RS41 Humidity Sensors Under a Ventilation Speed of 5 m s−1

open access: yesMeteorological Applications
Some commercial radiosondes use heating‐type humidity sensors to prevent condensation and improve response time during soundings. However, the heating process affects the temperature and relative humidity (RH) in the ground facilities where they are ...
Sung Min Kim   +6 more
doaj   +1 more source

Lung function association with outdoor temperature and relative humidity and its interaction with air pollution in the elderly

open access: yesEnvironmental Research, 2018
While the effects of weather variability on cardio‐respiratory mortality are well described, research examining the effects on morbidity, especially for vulnerable populations, is warranted.
J. Lepeule   +6 more
semanticscholar   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A Case Study of Assimilating Lightning-Proxy Relative Humidity with WRF-3DVAR

open access: yesAtmosphere, 2017
Lightning network data, considered as a useful supplement to radar observations, are a good indicator of severe convection, and has high temporal and spatial resolution.
Ying Wang   +5 more
doaj   +1 more source

Humidity's influence on visible region refractive index structure parameter $C_n^2$ [PDF]

open access: yes, 2006
In the infrared and visible bandpass, optical propagation theory conventionally assumes that humidity does not contribute to the effects of atmospheric turbulence on optical beams. While this assumption may be reasonable for dry locations, we demonstrate
Andreas   +14 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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