Results 71 to 80 of about 631,049 (308)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Dynamic characteristics of the LLNL precision engineering research lathe

, 2022
The dynamic characteristics of the Precision Engineering Research Lathe (PERL) have been investigated experimentally, up to a frequency of 1000 Hz. In successive tests the exciting force was applied to either the X slide or the (non-rotating) spindle ...
Roblee, J.W., Modemann, Karl, Franse, J.
core  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Demonstration of plate analysis, an algorithm for precise relative astrometry

Journal of Astronomical Telescopes, Instruments, and Systems
author's submit version, 31 pages, 11 figures, accepted for publication in Journal of Astronomical Telescopes, Instruments, and ...
Ohsawa, Ryou, Kawata, Daisuke, Kamizuka, Takafumi, Yamada, Yoshiyuki, Löffler, Wolfgang, Biermann, Michael   +5 more
openaire   +2 more sources

Precision - (relative) Recall curves.

, 2013
Precision - (relative)Recall curves for the RFF (Random-Forest-Filter) trained with the reduced feature set, the full feature set and different experimental setting (only physical interactions (PhyI), only genetic interactions (GenI) and all interactions
Robert Pesch (423138), Ralf Zimmer (21157)   +1 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Tracking Control of a Maglev Vibration Isolation System Based on a High-Precision Relative Position and Attitude Model

Sensors, 2019
The maglev vibration isolation system exhibits excellent micro-vibration isolation performance (0.01 Hz to 100 Hz band) in the space environment. However, a collision between the base and the floating platform may occur in an ultra-low frequency range (&#
Qianqian Wu, Bilong Liu, Ning Cui, Sifang Zhao   +3 more
doaj   +1 more source

A novel robust Gaussian filtering method for the characterization of surface generation in ultra-precision machining

, 2006
A lot of research work has been focused on the study of the surface generation mechanisms in order to predict the surface topography and provide the optimal machined parameters based on the experiential understanding of relationship of machined ...
Lee, W. B., To, S, Li, H, Jiang, XQ, Lee, WB, Li, Huifen, To, S., Jiang, X. Q., Cheung, CF, Cheung, C. F.   +9 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

An Examination of the Effectiveness of Precision Teaching

, 2009
This research examined the effect of adding precision teaching to an already used method of times table practice, compared practice with and without precision teaching, and finally compared precision teaching to rate building.
McQuarters, Desiree Julia Bettina
core