Results 91 to 100 of about 631,049 (308)
Between personalized and racialized precision medicine : a relative resources perspective
Since the completion of the first human genome sequencing project in 2003, the potential for incorporating genomics into clinical practice in the pursuit of precision medicine has garnered a great amount of attention and interest.
Sun, Shirley
core +1 more source
A practical demonstration on AMSU retrieval precision for upper tropospheric humidity by a non-linear multi-channel regression method [PDF]
A neural network algorithm inverting selected channels from the Advance Microwave Sounding Unit instruments AMSU-A and AMSU-B was applied to retrieve layer averaged relative humidity.
C. Jiménez +3 more
doaj
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Precision Teaching: Fast Practice or Merely More Practice Results in Better Learning?
Doughty, Chase and O'Shields (2004) reviewed the Precision Teaching literature which they point out claimed that Precision Teaching is superior in producing learning outcomes and they posed concerns about the lack of well designed research to support ...
Kong, Xiuyan
core
An investigation of how relative precision of target encoding influences metacognitive performance. [PDF]
Kellij S +4 more
europepmc +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The working accuracy of space optical payloads, sensitive components, greatly depends on the pointing accuracy and stability of the platform. This article establishes a mathematical model for relative position and attitude measurement based on PSD and ...
Mao Ye, Jianyu Wang
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Machining of Optical Surfaces in Brittle Materials using an Ultra-Precision Machine Tool [PDF]
Investigations of machining optical surfaces into brittle materials using an ultra precision machine tool are presented. The newly developed ultra precision NION machine is evaluated to gain a good appreciation of its operating performance.
Shore, Paul
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source

