Results 101 to 110 of about 3,528,903 (295)

A Theory of Rational Junk-Food Consumption [PDF]

An expected lifetime-utility maximizing diet of junk and health food is analyzed. The stationary junk-food consumption level is equal to the ratio of the recovery capacity of a perfectly healthy person to the sensitivity of her health to junk food.
Levy, Amnon
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Relative Sensitivity of Core-Needle Biopsy and Incisional Biopsy in the Diagnosis of Musculoskeletal Sarcomas. [PDF]

Cancers (Basel), 2021
Klein A, Fell T, Birkenmaier C, Fromm J, Jansson V, Knösel T, Dürr HR.   +6 more
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Comparison of the relative sensitivity of two dimensional personality models to the psychopathological symptoms: the section III DSM-5 maladaptive traits versus affective temperaments. [PDF]

BMC Psychiatry, 2022
Komasi S, Hemmati A, Rezaei F, Rahmani K, Miettunen J, Amianto F, Hopwood CJ.   +6 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Reduced Relative Sensitivity of the Elecsys SARS-CoV-2 Antigen Assay in Saliva Compared to Nasopharyngeal Swabs. [PDF]

Microorganisms, 2021
Audigé A, Böni J, Schreiber PW, Scheier T, Buonomano R, Rudiger A, Braun DL, Eich G, Keller DI, Hasse B, Berger C, Günthard HF, Manrique A, Trkola A, Huber M.   +14 more
europepmc   +1 more source

RELATIVE SENSITIVITY OF SELECTED DISTRIBUTED LAG ESTIMATORS TO MEASUREMENT AND SPECIFICATION ERROR [PDF]

Research Methods/ Statistical Methods,
Bauer, Larry L., Mundy, S. Darrell, Sappington, Charles B.   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Spontaneous creation of non-zero angular momentum modes in tunnel-coupled two-dimensional degenerate Bose gases

, 2010
We investigate the dynamics of two tunnel-coupled two-dimensional degenerate Bose gases. The reduced dimensionality of the clouds enables us to excite specific angular momentum modes by tuning the coupling strength, thereby creating striking patterns in ...
I. Lesanovsky, R. Folman, R. G. Scott, T. M. Fromhold, T. W. A. Montgomery   +4 more
core   +1 more source