Results 31 to 40 of about 436,600 (246)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Viscoelasticity of Edam cheese during its ripening

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2010
Series of the indentation of the ball (10 mm in diameter) by the constant speed into blocks of Edam cheese has been conducted. The indentation tests were performed at different speeds (1, 5, 10, 20 and 100 mm/min), and the corresponding force ...
Šárka Nedomová
doaj   +1 more source

Relaxing in Foam [PDF]

open access: yesPhysical Review Letters, 2003
We investigate the mechanical response of an aqueous foam, and its relation to the microscopic rearrangement dynamics of the bubble-packing structure. At rest, even though the foam is coarsening, the rheology is demonstrated to be linear. Under flow, shear-induced rearrangements compete with coarsening-induced rearrangements.
Gopal, A. D., Durian, Douglas J
openaire   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Effectiveness of the Nareswari Method (Breathing, Relaxation, and Coloring) on Reducing Anxiety Levels in Postpartum Mothers"

open access: yesProfessional Health Journal
Background: The postpartum period is a period of adaptation that is quite difficult for a mother. Various complaints can arise during the postpartum period, both physical and psychological complaints.
Alfadefi Khalifatunnisak   +2 more
doaj   +1 more source

Inhibition of Uterine Contractility by Thalidomide Analogs via Phosphodiesterase-4 Inhibition and Calcium Entry Blockade

open access: yesMolecules, 2016
Uterine relaxation is crucial during preterm labor. Phosphodiesterase-4 (PDE-4) inhibitors have been proposed as tocolytics. Some thalidomide analogs are PDE-4 inhibitors.
Eduardo Fernández-Martínez   +6 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Breaking the Cycle: How Fatigue, Cyberloafing, and Self-Regulation Influence Learning Satisfaction in Online Learning

open access: yesEducation Sciences
The transition to online learning has revolutionized educational experiences while introducing new challenges, such as managing fatigue and staying focused in digital environments. This study examines the relationship between fatigue, social cyberloafing,
Somya Agrawal, Shwetha M. Krishna
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

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