Results 51 to 60 of about 1,678,737 (297)

Inhibition of Uterine Contractility by Thalidomide Analogs via Phosphodiesterase-4 Inhibition and Calcium Entry Blockade

Molecules, 2016
Uterine relaxation is crucial during preterm labor. Phosphodiesterase-4 (PDE-4) inhibitors have been proposed as tocolytics. Some thalidomide analogs are PDE-4 inhibitors.
Eduardo Fernández-Martínez, Héctor Ponce-Monter, Luis E. Soria-Jasso, Mario I. Ortiz, José-Antonio Arias-Montaño, Guillermo Barragán-Ramírez, Cynthia Mayén-García   +6 more
doaj   +1 more source

Nonexponential Relaxation of Magnetization at the Resonant Tunneling Point under a Fluctuating Random Noise

, 2000
Nonexponential relaxation of magnetization at resonant tunneling points of nanoscale molecular magnets is interpreted to be an effect of fluctuating random field around the applied field.
Ao P., Barbara B., Chudnovsky E. M., De Raedt H., Dobrovitski V. V., Feller W., Fort A., Friedman J. R., Garanin D. A., Gunther L., Hams A., Hernandez J. M., Kayanuma Y., Landau L., Leggett A. G., Leuenberger M. N., Lionti F., Luis F., Miyashita S., Miyashita S., Miyashita S., Miyashita S., Nakamura Y., Ohm T., Perenboom J. A. A. J., Prokof'ev N. V., Saito K., Sangregorio C., Stückelberg E. C. G., Thomas L., Thomas L., Uhlenbeck G. E., Van Kampen N. G., Wernsdorfer W., Wernsdorfer W., Wernsdorfer W., Zener C.   +36 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Breaking the Cycle: How Fatigue, Cyberloafing, and Self-Regulation Influence Learning Satisfaction in Online Learning

Education Sciences
The transition to online learning has revolutionized educational experiences while introducing new challenges, such as managing fatigue and staying focused in digital environments. This study examines the relationship between fatigue, social cyberloafing,
Somya Agrawal, Shwetha M. Krishna
doaj   +1 more source

Resonant Relaxation in Stellar Systems [PDF]

, 1996
We demonstrate the existence of an enhanced rate of angular momentum relaxation in nearly Keplerian star clusters, such as those found in the centers of galactic nuclei containing massive black holes. The enhanced relaxation arises because the radial and
Rauch, Kevin P., Tremaine, Scott
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Integrative Therapies and Pediatric Inflammatory Bowel Disease: The Current Evidence

Children, 2014
Inflammatory bowel disease (IBD) primarily describes two distinct chronic conditions with unknown etiology, ulcerative colitis (UC) and Crohn’s disease (CD). UC is limited to the colon, while CD may involve any portion of the gastrointestinal tract from
Sanghamitra M. Misra
doaj   +1 more source

Nuclear spin warm-up in bulk n-GaAs

, 2016
We show that the spin-lattice relaxation in n-type insulating GaAs is dramatically accelerated at low magnetic fields. The origin of this effect, that cannot be explained in terms of well-known diffusion-limited hyperfine relaxation, is found in the ...
Dzhioev, R. I., Jouault, B., Kavokin, K. V., Korenev, V. L., Kotur, M., Vladimirova, M.   +5 more
core   +2 more sources

Equivalent relaxations of optimal power flow [PDF]

, 2014
Several convex relaxations of the optimal power flow (OPF) problem have recently been developed using both bus injection models and branch flow models.
Bose, Subhonmesh, Hassibi, Babak, Low, Steven H., Teeraratkul, Thanchanok   +3 more
core   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source