Results 51 to 60 of about 391,141 (265)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Gelation Time of Network-Forming Polymer Solutions with Reversible Cross-Link Junctions of Variable Multiplicity

Gels, 2023
The gelation time tg necessary for a solution of functional (associating) molecules to reach its gel point after a temperature jump, or a sudden concentration change, is theoretically calculated on the basis of the kinetic equation for the stepwise cross-
Fumihiko Tanaka
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Peculiarities of the process of switching polarization in polycrystalline thin films of lead zirconate-titanate [PDF]

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2018
The paper presents the results of a study of relaxation of the dielectric permittivities in constant electric fields upon switching the polarization of thin films of lead zirconate-titanate, crystallized at different annealing temperatures.
V.V. Ivanov, E.N. Golubeva, O.N. Sergeeva, G.M. Nekrasova, I.P. Pronin, D.A. Kiselev   +5 more
doaj   +1 more source

Artificial Periodic Irregularities and Temperature of the Lower Thermosphere

Atmosphere, 2023
The results of temperature measurements in the lower thermosphere at altitudes of 90–130 km by the method of resonant scattering of radio waves on artificial periodic inhomogeneities (APIs) of the ionospheric plasma are presented.
Nataliya V. Bakhmetieva, Gennadiy I. Grigoriev, Ilia N. Zhemyakov, Elena E. Kalinina   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Molecular mobility in crystallising aromatic thermoplastic polyimide R-BAPS

Physics of Complex Systems, 2020
The molecular mobility of the thermoplastic aromatic R-BAPS polyimide films based on 1,3-bis (3,3’-4,4’-dicarboxyphenoxy) benzene (dianhydride) and 4,4’-bis (4-aminophenoxy) biphenyl was studied using the dielectric method.
Наталья Алексеевна Никонорова, Алексей Андреевич Кононов, Рене Алехандро Кастро Арата   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Uncertainty estimates for magnetic relaxation times and magnetic relaxation parameters [PDF]

Physical Chemistry Chemical Physics, 2019
Uncertainties in magnetic relaxation times from AC magnetometry are derived and a program for obtaining them is described, allowing statistically meaningful magnetic relaxation parameterisation.
Daniel Reta, Nicholas F. Chilton
openaire   +4 more sources