Results 211 to 220 of about 21,756 (262)
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Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1990
1. Relaxin is a hormone of reproduction that appears to affect parturition, uterine accommodation, and sperm motility to varying degrees in many species. 2. All relaxins have the same two chain, disulfide-linked insulin-like structure and two arginine residues in the midregion of the B chain. 3.
C, Schwabe, E E, Büllesbach
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1. Relaxin is a hormone of reproduction that appears to affect parturition, uterine accommodation, and sperm motility to varying degrees in many species. 2. All relaxins have the same two chain, disulfide-linked insulin-like structure and two arginine residues in the midregion of the B chain. 3.
C, Schwabe, E E, Büllesbach
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Annals of the New York Academy of Sciences, 2009
Endometriosis is an important contributing factor to chronic pelvic pain and infertility. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) have each been implicated in the establishment of endometriotic lesions. Since relaxin regulates the expression of MMPs and VEGF in the endometrium, we tested the hypothesis that ...
MORELLI, S. S. +5 more
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Endometriosis is an important contributing factor to chronic pelvic pain and infertility. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) have each been implicated in the establishment of endometriotic lesions. Since relaxin regulates the expression of MMPs and VEGF in the endometrium, we tested the hypothesis that ...
MORELLI, S. S. +5 more
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Annual Review of Physiology, 1983
The author examines the investigative status of the peptide hormone relaxin, raising questions about and looking at the potential for the physiologic role of relaxin and the production of human relaxin for pharmacologic use.
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The author examines the investigative status of the peptide hormone relaxin, raising questions about and looking at the potential for the physiologic role of relaxin and the production of human relaxin for pharmacologic use.
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Endocrinology, 1953
IN 1926 Hisaw first demonstrated experimentally the relaxation of the pelvic ligaments of guinea pigs during estrus following the injection of blood serum from pregnant rabbits. Later work indicated a specific hormone, designated as relaxin, was responsible for the looseness of the symphysis pubis, since the effect was also observed following injection
R I, DORFMAN +2 more
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IN 1926 Hisaw first demonstrated experimentally the relaxation of the pelvic ligaments of guinea pigs during estrus following the injection of blood serum from pregnant rabbits. Later work indicated a specific hormone, designated as relaxin, was responsible for the looseness of the symphysis pubis, since the effect was also observed following injection
R I, DORFMAN +2 more
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Current Opinion in Chemical Biology, 2014
The relaxin subfamily of peptides within the human insulin superfamily consists of seven members including relaxin-2 and relaxin-3. The former is a pleiotropic hormone that is a vasodilator and cardiac stimulant in the cardiovascular system and an antifibrotic agent whereas the latter is primarily a neuropeptide involved in stress and metabolic control.
Hossain, MA, Wade, JD
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The relaxin subfamily of peptides within the human insulin superfamily consists of seven members including relaxin-2 and relaxin-3. The former is a pleiotropic hormone that is a vasodilator and cardiac stimulant in the cardiovascular system and an antifibrotic agent whereas the latter is primarily a neuropeptide involved in stress and metabolic control.
Hossain, MA, Wade, JD
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Relaxin, the Relaxin-Like Factor and Their Receptors
2008In 1926 Frederick Hisaw discovered a blood-borne factor in pregnant guinea pigs that would cause relaxation of the pubic symphysis in virgin females of the species. The relaxin-like factor gene (RLF), also known as insulin-like 3 (INSL3), was recovered from a library of testicular cDNA.
Christian, Schwabe, Erika E, Büllesbach
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1950
Publisher Summary This chapter discusses the physiology of relaxin. The discovery of relaxin was the outcome of studies concerning pelvic adaptations associated with parturition. Relaxin has been extracted from the corpora lutea of sows by several different methods.
F L, HISAW, M X, ZARROW
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Publisher Summary This chapter discusses the physiology of relaxin. The discovery of relaxin was the outcome of studies concerning pelvic adaptations associated with parturition. Relaxin has been extracted from the corpora lutea of sows by several different methods.
F L, HISAW, M X, ZARROW
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Relaxin and relaxin receptors in brain
2001Recent studies have shown that in addition to its role as a hormone of pregnancy, relaxin also has physiological functions in the central nervous system [1, 2, 3]. In the rat brain, relaxin binding sites have been located in the organum vasculosum of the lamina terminalis (OVLT) and the subfornical organ (SFO) [4] and centrally administered relaxin ...
Yean Yeow Tan +2 more
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Trends in Endocrinology & Metabolism, 2001
Abstract The Relaxin 2000: 3rd International Conference on Relaxin and Related Peptides meeting was held on 22–27 October 2000 in Broome, Australia.
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Abstract The Relaxin 2000: 3rd International Conference on Relaxin and Related Peptides meeting was held on 22–27 October 2000 in Broome, Australia.
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Australian and New Zealand Journal of Obstetrics and Gynaecology, 1981
Summary:: Relaxin is a polypeptide hormone, similar in structure to insulin and has been found in the female of all species studied. The corpus Iuteum of pregnancy is the main source of relaxin in many species but in others the decidua is apparently of greater importance. It has also been found in other tissues; e.g.
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Summary:: Relaxin is a polypeptide hormone, similar in structure to insulin and has been found in the female of all species studied. The corpus Iuteum of pregnancy is the main source of relaxin in many species but in others the decidua is apparently of greater importance. It has also been found in other tissues; e.g.
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