Enhancing Study Design and Analysis of MR Imaging Markers Through Measurement Error Modeling
ABSTRACT Background Measurement error in imaging reduces statistical power and potentially biases parameter estimation, compromising study reliability. Purpose To introduce a dual data collection design (reliability and main datasets) to quantify measurement error and apply regression calibration to correct error‐prone imaging markers, thereby ...
Xiaofeng Wang +8 more
wiley +1 more source
In Vivo Nanodiamond Quantum Sensing of Free Radicals in Caenorhabditis elegans Models
Free radicals are believed to play a secondary role in the cell death cascade associated with various diseases. In Huntington's disease (HD), the aggregation of polyglutamine (PolyQ) not only contributes to the disease but also elevates free radical ...
Siyu Fan +6 more
doaj +1 more source
Malignant gliomas are primary brain tumours with an infiltrative growth pattern, often with contrast enhancement on magnetic resonance imaging (MRI). However, it is well known that tumour infiltration extends beyond the visible contrast enhancement.
I. Blystad +7 more
semanticscholar +1 more source
Lumbar intervertebral discs T2 relaxometry and T1ρ relaxometry correlation with age in asymptomatic young adults [PDF]
To investigate the detection of intervertebral disc (IVD) composition aging-related changes using T2 and T1ρ relaxometry in vivo in asymptomatic young adults.We recruited ninety asymptomatic and young adults (42 men and 48 women) between 20 and 40 years old.
Rafael, Menezes-Reis +6 more
openaire +2 more sources
ABSTRACT Purpose To propose a signal acquisition and modeling framework for multi‐component tissue quantification that encompasses transmit field inhomogeneity, multi‐component relaxation and magnetization transfer (MT) effects. Theory and Methods By applying off‐resonance irradiation between excitation and acquisition within an RF‐spoiled gradient ...
Albert Jang +4 more
wiley +1 more source
Synthetic MRI for stroke: a qualitative and quantitative pilot study
Synthetic MR provides qualitative and quantitative multi-parametric data about tissue properties in a single acquisition. Its use in stroke imaging is not yet established.
Joachim André +2 more
doaj +1 more source
Tumour cell labelling by magnetic nanoparticles with determination of intracellular iron content and spatial distribution of the intracellular iron [PDF]
: Magnetically labelled cells are used for in vivo cell tracking by MRI, used for the clinical translation of cell-base therapies. Studies involving magnetic labelled cells may include separation of labelled cells, targeted delivery and controlled ...
Alexiou +41 more
core +5 more sources
Technical Review of Magnetic Resonance Fingerprinting Applications in Cerebral Physiology
ABSTRACT Magnetic resonance fingerprinting (MRF) enables quantitative MRI by allowing the simultaneous mapping of multiple tissue properties through innovative acquisition and computational methods. This review focuses on the application of MRF techniques to cerebral physiology, emphasizing advancements in vascular imaging and the integration of ...
Chieh‐Te Lin +2 more
wiley +1 more source
Relaxivity Modulation of Gd-HPDO3A-like Complexes by Introducing Polar and Protic Peripheral Groups
In the last three decades, high-relaxivity Magnetic Resonance Imaging (MRI) contrast agents (CAs) have been intensively sought, aiming at a reduction in the clinically injected dose while maintaining the safety of the CA and obtaining the same ...
Sara Camorali +3 more
doaj +1 more source
Synthetic quantitative MRI through relaxometry modelling
AbstractQuantitative MRI (qMRI) provides standardized measures of specific physical parameters that are sensitive to the underlying tissue microstructure and are a first step towards achieving maps of biologically relevant metrics through in vivo histology using MRI.
Martina F. Callaghan +2 more
openaire +4 more sources

