Results 131 to 140 of about 183,105 (231)

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Architected Load Paths Enable Stiffening and Motion Programming in Soft Pneumatic Actuators

Advanced Science, EarlyView.
A single MARS template introduces an architected reinforcement strategy for programmable soft pneumatic actuators through internal structural organization and selective beam removal. This monolithic architecture enables deformation reconfiguration from continuous bending to joint‐like articulation and torsional motion, allowing one compliant platform ...
Jie Wang, Yuwen Wu, Yuze Zhang, Ye Wei, Yuting Ma, Yingxiang Liu, Kai Guo   +6 more
wiley   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

Advanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu, Xin Yuan, Zilong He, Hong Jin, Jiayi Tian, Cong Chen, Yuanjing Liu, Xiang Zhang, Shidan Wen, Emilio Kropff, Chenglin Miao   +10 more
wiley   +1 more source

Secondary-Amine Relay Enables Lysine-Directed Multicomponent Functionalization of Peptides. [PDF]

JACS Au
Ren C, Zhang M, Jiang T, Wan F, Lv Y, Yang L, Li C.   +6 more
europepmc   +1 more source

Intrinsic Superprotonic Conduction in Metal‐Free Hydrogen‐Bonded Organic–Inorganic Frameworks

Advanced Science, EarlyView.
A simple hybridization strategy yields a suite of metal‐free hydrogen‐bonded organic‐inorganic frameworks (HOIFs) with dense, uninterrupted hydrogen‐bonded networks that possess intrinsically high superprotonic conductivity, establishing a versatile and scalable platform for high‐performance solid‐state proton conductors.
Jin Chen, Yongqiang Cheng, Simon J. Teat, Gobin Raj Acharya, Roknuzzaman Roknuzzaman, Wensong Yu, Yucong Xia, Weston C. Swallow, Xiaoying Huang, Xiaodong Yang, Thomas J. Emge, Kui Tan, Andrew J. Nieuwkoop, Lawrence J. Williams, Jing Li   +14 more
wiley   +1 more source

Attack-Aware Secure Sensor Transmission Using Pinching- Antenna Systems and Trust-Guided Cooperative Jamming. [PDF]

Sensors (Basel)
Qian S, Li Z, Cheng M.
europepmc   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

Vision-Assisted UAV Relay Triggering for Proactive Blockage Mitigation in Air-Ground Integrated mmWave V2X Networks. [PDF]

Sensors (Basel)
Wang Y, Chen W, Kong L, Wang X, Weng W, Liu Y, Gao Y, Zhang X.   +7 more
europepmc   +1 more source

Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis

Advanced Science, EarlyView.
Conjugated polymer‐supported bioelectrochemical systems are shown to enhance microbial electrosynthesis by triggering coordinated electrochemical, transcriptional, post‐transcriptional (sRNA), metabolic, and protein‐level responses. Integrated multi‐omics and electrochemical analyses reveal selective physiological remodeling associated with improved ...
David Ohayon, Yuanmei Liang, Zexuan Wang, Jee Loon Foo, Glenn Quek, Samantha R. McCuskey, Zhongxin Chen, Matthew Wook Chang, Guillermo C. Bazan   +8 more
wiley   +1 more source