Results 141 to 150 of about 183,105 (231)

A Molecularly Defined Midbrain Circuit Mechanism for Sound‐Driven Defensive Behavior and Anxiety

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing the Cbln2+ ICx–dPAG circuit for sound‐driven defensive and anxiety‐like behaviors. ABSTRACT The innate defense behaviors in response to threatening sounds play a fundamental role in survival. However, the neural circuits that detect threat‐relevant auditory cues and transform them into defensive behaviors remain poorly defined.
Jie Cao   +8 more
wiley   +1 more source

A low-cost modular PCB assembly for functional and in-circuit testing. [PDF]

open access: yesHardwareX
Puentes-Conde GM   +5 more
europepmc   +1 more source

Single‐Pulse Femtosecond Laser 3D Multi‐Foci Light‐Field Engineering via Multi‐Layer Noise Threshold Filtering

open access: yesAdvanced Science, EarlyView.
This study presents a single‐pulse femtosecond laser strategy for three‐dimensional multi‐foci light‐field shaping and high‐throughput micro/nano manufacturing. The multi‐layer noise threshold filtering algorithm improves focal quality, while the multi‐layer over‐sampling algorithm increases focal density.
Shouyu Wu   +9 more
wiley   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

open access: yesAdvanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko   +5 more
wiley   +1 more source

Iterating the transient light transport matrix for non-line-of-sight imaging. [PDF]

open access: yesNat Commun
Sultan T   +6 more
europepmc   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

open access: yesAdvanced Science, EarlyView.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li   +11 more
wiley   +1 more source

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

open access: yesAdvanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy