Results 91 to 100 of about 1,548,001 (241)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
UST pipeline (Online); Underground Storage Tank pipeline; Welcome to the UST pipeline--
, 2000 Irregular; Electronic coverage as of Apr. 5, 2010: Feb. 2000-; Mar. 2006- : News from the Petroleum UST Release Compensation Board.; Feb. 2000-Mar. 2006: Arranged by date; each article, of each issue, is an individual PDF file.; Description based on: Feb.
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Signal Transduction and Targeted TherapyThe intricate tumor microenvironment presents formidable obstacles to the efficacy of adoptive T cell therapy in the management of solid tumors by limiting the infiltration and inducing exhaustion of the transferred T cells.
Chaojie Zhu +17 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
big-unibo/stink-bug: Main release
<p>Release of the project</p ...
Semantic Release Bot +2 more
core +1 more source
Press Release N°08/2019 : African Union Unveils a Statue of Former Ethiopian Emperor Haile Selassie I [PDF]
, 2019 Press release on the unveiling of the statue of Emperor Haile Selassie at the African union Headquarters in Addis Ababa, Ethiopia on the 10th of February ...
African Union
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Unveiling the bioactive landscape of drug inactive ingredients (DIGs) using deep transfer learning
Acta Pharmaceutica Sinica BIn a drug product, the major components by mass are the drug inactive ingredients (DIGs), which raises great concerns about their unwanted effects and clinical toxicities.
Minjie Mou +16 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
In vitro Evaluation of a Multiple-Unit Formulation for Oral Colonic Release of Insulin
, 2013 SUMMARY A multiple-unit formulation for time-dependent colonic release of insulin was prepared and evaluated. Minitablet cores containing the protein drug along with a permeation enhancer, sodium glycocholate, in a 1:10 ratio were in turn spray-coated ...
A. Maroni +6 more
core +2 more sources