Results 51 to 60 of about 1,717,917 (266)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Stock Markets and Stress Test Announcements: Evidence from European Banks

open access: yesEconomies
This paper examines the market reaction to the European bank stress test announcement and results release events. Using event study methodology (calculating abnormal returns on a three-day period around the event dates), we find that the market reacts ...
Christos Floros   +2 more
doaj   +1 more source

Optimal Results and Numerical Simulations for Flow Shop Scheduling Problems

open access: yesJournal of Applied Mathematics, 2012
This paper considers the m-machine flow shop problem with two objectives: makespan with release dates and total quadratic completion time, respectively. For Fm|rj|Cmax, we prove the asymptotic optimality for any dense scheduling when the problem scale is
Tao Ren, Yuandong Diao, Xiaochuan Luo
doaj   +1 more source

Heuristics for the Early/Tardy Scheduling Problem with Release Dates [PDF]

open access: yes
In this paper we consider the single machine earliness/tardiness scheduling problem with di?erent release dates and no unforced idle time. We analyse the performance of several dispatch rules, a greedy procedure and a decision theory local search ...
Rui A. F. S. Alves, Jorge M. S. Valente
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Beam search algorithms for the early/tardy scheduling problem with release dates [PDF]

open access: yes
In this paper we consider the single machine earliness/tardiness scheduling problem with di?erent release dates and no unforced idle time. We present several heuristic algorithms based on the beam search technique. These algorithms include classical beam
Rui A. F. S. Alves, Jorge M. S. Valente
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Survey of common factors to determine suitability for work release

open access: yes, 1969
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF cover (viewed on June 20, 2016)."Work release

core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Dates and Times Made Easy with lubridate [PDF]

open access: yes
This paper presents the lubridate package for R, which facilitates working with dates and times. Date-times create various technical problems for the data analyst. The paper highlights these problems and offers practical advice on how to solve them using
Hadley Wickham, Garrett Grolemund
core  

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