Results 81 to 90 of about 1,717,917 (266)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Due Dates, January, 1991

open access: yes, 2018
Due Dates was a public, supplemental publication of the Toledo Lucas County Public Library that first appeared in January of 1988. Its last issue was published alongside the last The County Line and was dated December 1992 and January 1993.
Toledo Lucas County Public Library
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

The genetic base of Brazilian soybean cultivars: evolution over time and breeding implications

open access: yesGenetics and Molecular Biology, 2013
Genetic diversity is essential for crop breeding and one way to estimate it is through the concept of genetic base, which can be defined as the number of ancestors and their relative genetic contributions (RGC) to each cultivar.
Philip Traldi Wysmierski   +1 more
doaj  

Due Dates, November, 1989

open access: yes, 2018
Due Dates was a public, supplemental publication of the Toledo Lucas County Public Library that first appeared in January of 1988. Its last issue was published alongside the last The County Line and was dated December 1992 and January 1993.
Toledo Lucas County Public Library
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Due Dates, September, 1988

open access: yes, 2018
Due Dates was a public, supplemental publication of the Toledo Lucas County Public Library that first appeared in January of 1988. Its last issue was published alongside the last The County Line and was dated December 1992 and January 1993.
Toledo Lucas County Public Library
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Due Dates, October, 1988

open access: yes, 2018
Due Dates was a public, supplemental publication of the Toledo Lucas County Public Library that first appeared in January of 1988. Its last issue was published alongside the last The County Line and was dated December 1992 and January 1993.
Toledo Lucas County Public Library
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

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