Results 151 to 160 of about 2,830,468 (238)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

How Do Information Content and Language Style Relate to Disaster Information Dissemination? The Moderating Role of User Involvement. [PDF]

Behav Sci (Basel)
Chen J, Lu Y.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Labeled ingredient composition and literature-reported hazard signals in children's toothpastes available through selected UAE retail sources. [PDF]

Front Oral Health
Manla S, Al Halabi M, Senok A, Nassar R, Salami A, Hussein I, Kowash M.   +6 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Photodynamic Inactivation Mediated by Endogenous Porphyrins of Corynebacterium diphtheriae in Planktonic and Biofilm Forms

ACS Omega
Gabriela Batista Alves, Mônica Regina da Costa Marques Calderari, Eduardo Nunes da Fonseca, Lincoln de Oliveira Sant’anna, Louisy Sanches dos Santos, Ana Luiza de Mattos-Guaraldi   +5 more
doaj   +1 more source

Scaling vision models does not consistently improve localisation-based explanation quality. [PDF]

Sci Rep
Cedro M, Chlebus M.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Relevance and Linguistic Meaning The Semantics and Pragmatics of Discourse Markers

A study of the analysis of discourse markers (words like 'so', 'however', and 'well').Cover -- Half-title -- Series-title -- Title -- Copyright -- Dedication -- Contents -- Acknowledgements -- Introduction -- 1 Meaning and truth -- 1.1 Introduction -- 1 ...
Ewen, C. J., Bresnan, J., Rice, K., Comrie, B., Dressler, W., Austin, P., Lass, R., Lightfoot, D., Crain, S., Blakemore, Diane.   +9 more
core  

Perceived rivalry in intergroup conflict. [PDF]

Front Psychol
Reinhard DA, Gianiodis PT, Hirschberger G, Leidner B.   +3 more
europepmc   +1 more source