Results 41 to 50 of about 239,051 (251)
How translations are willed into existence
Слово.ру: балтийский акцент, 2019 This paper will argue that translations are willed into existence in three conceivable ways: pull, push and shuffle. Pull is the most intuitive form. It corresponds, for example, to a publishing house that decides to translate a foreign novel.
Stecconi, U.
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Rapid Access to Scalar Implicatures in Adjacency Pair Contexts: Experimental Evidence in Spanish
Languages, 2019 A conversational implicature arises when there is a gap between the syntactically and semantically encoded meaning of a sentence and the pragmatic meaning that is inferred in an actual communicative situation. Several experimental studies have approached
Rodrigo Loredo +2 more
doaj +1 more source
The European Journal of Humour Research, 2022 This paper reports on an exploratory study examining joke identification, appreciation and comprehension by Spanish intermediate ESL learners. The study is based on a relevance-theoretic classification of jokes, which assumes that humorousness results ...
Santiago Arróniz Parra +1 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
REFERENCE THEORIES AND THE RELEVANCE OF DESCRIPTIONS [PDF]
Manuscrito, 2020 Abstract Mario Gómez-Torrente (2019) is a fundamental contribution to the issue of reference and especially of reference fixing. In this article I will focus on some questions addressed in it, especially on the relationships between some components of Kripke’s, Putnam’s and Gómez-Torrente’s theories of reference fixing as well as on the relevance of ...
openaire +4 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source