Results 31 to 40 of about 374,715 (265)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Study on the operating characteristics of a compound automatic transfer switch based on forced current commutation

open access: yesThe Journal of Engineering, 2019
The automatic transfer switch can solve the problem of voltage drop and instantaneous power interruption, which is one of the most reliable and economical ways to improve the reliability and quality of the power supply.
Qu Lu   +5 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Review of approaches to improving the reliability and efficiency of technical operation of motor vehicles, taking into account the validity of engineering solutions

open access: yesТехнічна інженерія
The article presents an overview analysis of approaches to ensuring the reliability and efficiency of technical operation of motor vehicles through the implementation of engineering solutions considered as an element of a controlled dynamic system ...
V.V. Krivda   +4 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Study on Sealing Reliability of Deep-sea Underwater Gate Valve and Actuator

open access: yesShiyou jixie, 2023
Deep-sea underwater gate valve and actuator are indispensable devices in subsea production system such as subsea Christmas tree, flow line and subsea manifold system.Their sealing reliability is crucial to their service performance and life, and is also ...
Wan Chunyan   +5 more
doaj  

City utility tunneling designing method based on “support-rock mass” interaction

open access: yesГорные науки и технологии, 2018
At present time, megacities face acute problem of construction of tunnels for laying utility networks. In such large cities as Hanoi, Ho Chi Minh, there are still no solutions to the problem of laying technical pipelines, power cables, water supply and ...
Duyen Phong Nguyen   +3 more
doaj   +1 more source

The maison europeenne des procedes innovants (MEPI),an example of piloting and industrial demonstration facility for the green process engineering [PDF]

open access: yes, 2009
. Economical, energy savings and environmental challenges require an actual technological breakthrough in process engineering, aiming with productivity, product quality, safety and reliability objectives.
Caze, Pierre   +5 more
core  

Reliability-based economic model predictive control for generalized flow-based networks including actuators' health-aware capabilities [PDF]

open access: yes, 2016
This paper proposes a reliability-based economic model predictive control (MPC) strategy for the management of generalized flow-based networks, integrating some ideas on network service reliability, dynamic safety stock planning, and degradation of ...
Grosso Pérez, Juan Manuel   +2 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy