Results 91 to 100 of about 5,008,228 (330)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Optimization of Spare Parts Varieties Based on Stochastic DEA Model
IEEE Access, 2018 Accurate inventory management starts with the scientific and rational classification of numerous varieties of spare parts. This paper presents a stochastic data envelopment analysis (DEA) model to address the problem of optimization of spares varieties ...
Meilin Wen +4 more
doaj +1 more source
High-reliability release mechanism [PDF]
, 1971 Release mechanism employing simple clevis fitting in combination with two pin-pullers achieves high reliability degree through active mechanical redundancy. Mechanism releases solar arrays. It is simple and inexpensive and performs effectively. It adapts
Paradise, J. J.
core +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Entropy, 2019 In this study, we investigated the time-varying capacitated lot-sizing problem under a fast-changing production environment, where production factors such as the setup costs, inventory-holding costs, production capacities, or even material prices may be ...
Meng You +5 more
doaj +1 more source
Discussed here is failure physics, the study of how products, hardware, software, and systems fail and what can be done about it. The intent is to impart useful information, to extend the limits of production capability, and to assist in achieving low ...
Barber, Frank J. +5 more
core +1 more source
Proceedings of the international conference on Reliable software -, 1975 This paper surveys the problems of achieving data reliability, and finds them more severe than those of program reliability. It then outlines some of the conceptual and methodological tools which are available for the solution of these problems, including the concept of type, direct product, union, sequence, recursion and mapping.
openaire +3 more sources
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A Machine-Learning-Based Prediction Method for Hypertension Outcomes Based on Medical Data
Diagnostics, 2019 The outcomes of hypertension refer to the death or serious complications (such as myocardial infarction or stroke) that may occur in patients with hypertension.
Wenbing Chang +6 more
doaj +1 more source