Results 91 to 100 of about 1,633,391 (296)

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Magnetostrictive bi-perceptive flexible sensor for tracking bend and position of human and robot hand

Scientific Reports
The sensor that simultaneously perceives bending strain and magnetic field has the potential to detect the finger bending state and hand position of the human and robot.
Qian Wang, Mingming Li, Pingping Guo, Liang Gao, Ling Weng, Wenmei Huang   +5 more
doaj   +1 more source

Reliability, validity and measurement invariance of the Simplified Medication Adherence Questionnaire (SMAQ) among HIV-positive women in Ethiopia: a quasi-experimental study [PDF]

, 2020
Chris B. Agala, Bruce J. Fried, James C. Thomas, Heidi W. Reynolds, Kristen Hassmiller Lich, Kathryn Whetten, Catherine Zimmer, J Morrissey   +7 more
openalex   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Reliability of anthropometric measurements inEuropean preschool children: theToyBox‐study [PDF]

, 2014
Pilar De Miguel‐Etayo, M.I. Mesana, Greet Cardon, Ilse De Bourdeaudhuij, Magdalena Góźdź, Piotr Socha, M. Lateva, Violeta Iotova, Berthold Koletzko, K. Duvinage, Odysseas Androutsos, Yannis Μanios, Luís A. Moreno   +12 more
openalex   +1 more source

A 1036-F²/Bit High Reliability Temperature Compensated Cross-Coupled Comparator-Based PUF [PDF]

, 2020
Qiang Zhao, Yiheng Wu, Xiaojin Zhao, Yuan Cao, Chip-Hong Chang   +4 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug‐Induced Liver Injury Network (DILIN) [PDF]

, 2014
Paul H. Hayashi, Huiman X. Barnhart, Robert J. Fontana, Naga Chalasani, Timothy J. Davern, Jayant A. Talwalkar, K. Rajender Reddy, Andrew Stolz, Jay H. Hoofnagle, Don C. Rockey   +9 more
openalex   +1 more source