Results 71 to 80 of about 1,489,819 (267)

A Machine-Learning-Based Prediction Method for Hypertension Outcomes Based on Medical Data

Diagnostics, 2019
The outcomes of hypertension refer to the death or serious complications (such as myocardial infarction or stroke) that may occur in patients with hypertension.
Wenbing Chang, Yinglai Liu, Yiyong Xiao, Xinglong Yuan, Xingxing Xu, Siyue Zhang, Shenghan Zhou   +6 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Generative Adversarial Network-Based Intelligent Fault Diagnosis Method for Rotating Machinery Under Small Sample Size Conditions

IEEE Access, 2019
Rotating machinery plays a key role in mechanical equipment, and the fault diagnosis of rotating machinery is a popular research topic. To overcome the dependency on expert knowledge regarding conventional time-frequency analysis diagnosis methods ...
Yu Ding, Liang Ma, Jian Ma, Chao Wang, Chen Lu   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Shape-position perceptive fusion electronic skin with autonomous learning for gesture interaction

Microsystems & Nanoengineering
Wearable devices, such as data gloves and electronic skins, can perceive human instructions, behaviors and even emotions by tracking a hand's motion, with the help of knowledge learning.
Qian Wang, Mingming Li, Pingping Guo, Liang Gao, Ling Weng, Wenmei Huang   +5 more
doaj   +1 more source

Health assessment of a brushless direct current motor stator using a physics-informed long short-term memory network

International Journal of Electrical Power & Energy Systems
The brushless direct-current (BLDC) motor is widely regarded as a promising and versatile electronically controlled motor. Ensuring its reliable operation is crucial for maintaining production efficiency and safety.
Yi Ren, Runfei Yi, Zhaoxin Lian, Quan Xia, Dezhen Yang, Bo Sun, Qiang Feng   +6 more
doaj   +1 more source

Optimization of Spare Parts Varieties Based on Stochastic DEA Model

IEEE Access, 2018
Accurate inventory management starts with the scientific and rational classification of numerous varieties of spare parts. This paper presents a stochastic data envelopment analysis (DEA) model to address the problem of optimization of spares varieties ...
Meilin Wen, Tianpei Zu, Miaomiao Guo, Rui Kang, Yi Yang   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source